INTRODUCTION: Unwanted changes in body composition, as well as their impact on these people's quality of life, have been little investigated in patients with breast cancer. OBJECTIVE: [corrected] To assess the role of body composition on quality of life and the impact of chemotherapy on both, in women with breast cancer. METHODS: It was assessed prospectively women with breast cancer in a cohort of patients undergoing chemotherapy. Body composition was estimated through bioelectrical impedance. The quality of life was evaluated using the World Health Organization quality of life questionnaire. RESULTS: This study assessed 70 women, 77 and 73% of those were initially overweight and had excess of body fat, respectively. There was a significant increase in fat-free mass (p > 0.001), body mass index (p = 0.03) and weight (p = 0.02) while quality of life stayed the same during the study. Moreover, women with excess of body fat showed a significantly lower initial general health score, compared to those with normal body fat (p = 0.02). CONCLUSIONS: Chemotherapy proved to be a potential inducer in the weight gain in this population. We highlight the importance of further investigation about the impact of body fat accumulation on those women's quality of life.
INTRODUCTION: Unwanted changes in body composition, as well as their impact on these people's quality of life, have been little investigated in patients with breast cancer. OBJECTIVE: [corrected] To assess the role of body composition on quality of life and the impact of chemotherapy on both, in women with breast cancer. METHODS: It was assessed prospectively women with breast cancer in a cohort of patients undergoing chemotherapy. Body composition was estimated through bioelectrical impedance. The quality of life was evaluated using the World Health Organization quality of life questionnaire. RESULTS: This study assessed 70 women, 77 and 73% of those were initially overweight and had excess of body fat, respectively. There was a significant increase in fat-free mass (p > 0.001), body mass index (p = 0.03) and weight (p = 0.02) while quality of life stayed the same during the study. Moreover, women with excess of body fat showed a significantly lower initial general health score, compared to those with normal body fat (p = 0.02). CONCLUSIONS: Chemotherapy proved to be a potential inducer in the weight gain in this population. We highlight the importance of further investigation about the impact of body fat accumulation on those women's quality of life.
Authors: S Gérard; D Bréchemier; A Lefort; S Lozano; G Abellan Van Kan; T Filleron; L Mourey; C Bernard-Marty; M E Rougé-Bugat; V Soler; B Vellas; M Cesari; Y Rolland; L Balardy Journal: J Nutr Health Aging Date: 2016 Impact factor: 4.075
Authors: Vengadesan Kowshik; Subramanian Velkumary; Pooja Sethi; Jothi Marie Feula; Soundirarajan Subhashri; Manikandan Abirami Journal: J Family Med Prim Care Date: 2021-02-27