Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Temperature-induced transitory and steady-state changes in the calcium current of guinea pig ventricular myocytes.

Literature DB >> 2415920

Temperature-induced transitory and steady-state changes in the calcium current of guinea pig ventricular myocytes.

A Cavalié, T F McDonald, D Pelzer, W Trautwein.

Abstract

ICa was recorded in guinea pig ventricular myocytes using the whole-cell voltage-clamp technique. The shape of the I-V relation was unaffected by temperature (21-37 degrees C) but there were large changes in ICa amplitude and time course. Steady-state responses indicated Q10's of 2.96 +/- 0.14 (amplitude), 2.52 +/- 0.13 (time to peak), and 2.82 +/- 0.28 (T1/2 inactivation) (mean +/- SD, n = 6). Quick changes in temperature (T1/2 less than 30 s) induced pronounced deviations from the steady-state Q10 relations (early depression, compensatory overshoot). Thus, cardiac ICa differs from other currents in having a high amplitude-Q10 and an oscillatory response to rapid temperature changes.

Entities: Chemical Disease Species

Mesh：

Substances：
Ion Channels
Calcium

Year: 1985 PMID： 2415920 DOI： 10.1007/bf00582574

Source DB: PubMed Journal: Pflugers Arch ISSN： 0031-6768 Impact factor: 3.657

12 in total

1. Inactivation of calcium channels in mammalian heart cells: joint dependence on membrane potential and intracellular calcium.

Authors: K S Lee; E Marban; R W Tsien
Journal: J Physiol Date: 1985-07 Impact factor: 5.182

2. Laser temperature-jump technique for relaxation studies of the ionic conductances in myelinated nerve fibers.

Authors: L E Moore; J P Holt; B D Lindley
Journal: Biophys J Date: 1972-02 Impact factor: 4.033

3. Characteristics of the second inward current in cells isolated from rat ventricular muscle.

Authors: M R Mitchell; T Powell; D A Terrar; V W Twist
Journal: Proc R Soc Lond B Biol Sci Date: 1983-10-22

4. Voltage clamp measurements of sodium channel properties in rabbit cardiac Purkinje fibres.

Authors: T J Colatsky
Journal: J Physiol Date: 1980-08 Impact factor: 5.182

5. Temperature dependence of the sodium channel gating kinetics in the node of Ranvier.

Authors: C A Collins; E Rojas
Journal: Q J Exp Physiol Date: 1982-01

6. Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea-pig heart.

Authors: B Sakmann; G Trube
Journal: J Physiol Date: 1984-02 Impact factor: 5.182

7. Membrane currents in cat myocardium: separation of inward and outward components.

Authors: T F McDonald; W Trautwein
Journal: J Physiol Date: 1978-01 Impact factor: 5.182

8. Calcium current activation kinetics in neurones of the snail Lymnaea stagnalis.

Authors: L Byerly; P B Chase; J R Stimers
Journal: J Physiol Date: 1984-03 Impact factor: 5.182

9. Calcium inward current and related charge movements in the membrane of snail neurones.

Authors: P G Kostyuk; O A Krishtal; V I Pidoplichko
Journal: J Physiol Date: 1981-01 Impact factor: 5.182

10. Patch and whole cell calcium currents recorded simultaneously in snail neurons.

Authors: H D Lux; A M Brown
Journal: J Gen Physiol Date: 1984-05 Impact factor: 4.086

25 in total

1. Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes.

Authors: T F McDonald; A Cavalié; W Trautwein; D Pelzer
Journal: Pflugers Arch Date: 1986-05 Impact factor: 3.657

2. Fast and slow gating behaviour of single calcium channels in cardiac cells. Relation to activation and inactivation of calcium-channel current.

Authors: A Cavalié; D Pelzer; W Trautwein
Journal: Pflugers Arch Date: 1986-03 Impact factor: 3.657

3. Temperature dependence of multiple high voltage activated Ca2+ channels in chick sensory neurones.

Authors: P Acerbo; M Nobile
Journal: Eur Biophys J Date: 1994 Impact factor: 1.733

4. Temperature sensitivity of Ca currents in chick sensory neurones.

Authors: M Nobile; E Carbone; H D Lux; H Zucker
Journal: Pflugers Arch Date: 1990-03 Impact factor: 3.657

5. L-type Ca-channels: similar Q10 of Ca-, Ba- and Na-conductance points to the importance of ion-channel interaction.

Authors: U Klöckner; A Schiefer; G Isenberg
Journal: Pflugers Arch Date: 1990-02 Impact factor: 3.657

6. Involvement of the calcium inward current in cardiac impulse propagation: induction of unidirectional conduction block by nifedipine and reversal by Bay K 8644.

Authors: S Rohr; J P Kucera
Journal: Biophys J Date: 1997-02 Impact factor: 4.033