| Literature DB >> 24158312 |
Yulong Zhang1, Xiaohua Liu, Xiaohu Zhao, Jianlin Zhang, Lin Zhou, Lili Lin, Xiaoming Feng.
Abstract
An efficient catalytic asymmetric intermolecular C2 Friedel-Crafts alkylation reaction between N-methyl skatole and β,γ-unsaturated α-ketoesters has been realized by a chiral N,N'-dioxide-Ni(II) complex. The corresponding indole derivatives were obtained in good yield (up to 96%) with excellent enantioselectivities (up to 99% ee) under mild reaction conditions.Entities:
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Year: 2013 PMID： 24158312 DOI： 10.1039/c3cc45665j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222