| Literature DB >> 24156811 |
Abstract
Chromosome segregation requires the removal of cohesion and catenation between sister chromosomes, two physical linkages established during DNA replication. Two new studies reveal that, among other functions, the wings apart-like protein (Wapl) coordinates cohesin removal with decatenation of sister chromosomes during mitosis in mammalian cells.Entities:
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Year: 2013 PMID： 24156811 DOI： 10.1016/j.cub.2013.09.030
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834