Literature DB >> 24155555

Laser ion acceleration toward future ion beam cancer therapy - Numerical simulation study -.

Shigeo Kawata1, Takeshi Izumiyama, Toshihiro Nagashima, Masahiro Takano, Daisuke Barada, Qing Kong, Yan Jun Gu, Ping Xiao Wang, Yan Yun Ma, Wei Min Wang.   

Abstract

BACKGROUND: Ion beam has been used in cancer treatment, and has a unique preferable feature to deposit its main energy inside a human body so that cancer cell could be killed by the ion beam. However, conventional ion accelerator tends to be huge in its size and its cost. In this paper a future intense-laser ion accelerator is proposed to make the ion accelerator compact. SUBJECTS AND METHODS: An intense femtosecond pulsed laser was employed to accelerate ions. The issues in the laser ion accelerator include the energy efficiency from the laser to the ions, the ion beam collimation, the ion energy spectrum control, the ion beam bunching and the ion particle energy control. In the study particle computer simulations were performed to solve the issues, and each component was designed to control the ion beam quality.
RESULTS: When an intense laser illuminates a target, electrons in the target are accelerated and leave from the target; temporarily a strong electric field is formed between the high-energy electrons and the target ions, and the target ions are accelerated. The energy efficiency from the laser to ions was improved by using a solid target with a fine sub-wavelength structure or by a near-critical density gas plasma. The ion beam collimation was realized by holes behind the solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching were successfully realized by a multi-stage laser-target interaction.
CONCLUSIONS: The present study proposed a novel concept for a future compact laser ion accelerator, based on each component study required to control the ion beam quality and parameters.

Entities:  

Keywords:  Intense pulsed laser; laser ion acceleration; laser ion beam cancer therapy; laser plasma interaction

Year:  2013        PMID: 24155555      PMCID: PMC3806068          DOI: 10.3136/islsm.22.103

Source DB:  PubMed          Journal:  Laser Ther        ISSN: 0898-5901


  14 in total

1.  Fast ignition by intense laser-accelerated proton beams.

Authors:  M Roth; T E Cowan; M H Key; S P Hatchett; C Brown; W Fountain; J Johnson; D M Pennington; R A Snavely; S C Wilks; K Yasuike; H Ruhl; F Pegoraro; S V Bulanov; E M Campbell; M D Perry; H Powell
Journal:  Phys Rev Lett       Date:  2001-01-15       Impact factor: 9.161

2.  High density collimated beams of relativistic ions produced by petawatt laser pulses in plasmas

Authors: 
Journal:  Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics       Date:  2000-11

3.  Origin of protons accelerated by an intense laser and the dependence of their energy on the plasma density.

Authors:  Takashi Nakamura; Shigeo Kawata
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2003-02-06

4.  Influence of the laser prepulse on proton acceleration in thin-foil experiments.

Authors:  M Kaluza; J Schreiber; M I K Santala; G D Tsakiris; K Eidmann; J Meyer-Ter-Vehn; K J Witte
Journal:  Phys Rev Lett       Date:  2004-07-20       Impact factor: 9.161

5.  Multi-MeV proton source investigations in ultraintense laser-foil interactions.

Authors:  M Borghesi; A J Mackinnon; D H Campbell; D G Hicks; S Kar; P K Patel; D Price; L Romagnani; A Schiavi; O Willi
Journal:  Phys Rev Lett       Date:  2004-02-05       Impact factor: 9.161

6.  Laser-accelerated protons with energy-dependent beam direction.

Authors:  F Lindau; O Lundh; A Persson; P McKenna; K Osvay; D Batani; C-G Wahlström
Journal:  Phys Rev Lett       Date:  2005-10-19       Impact factor: 9.161

7.  Quasimonoenergetic deuteron bursts produced by ultraintense laser pulses.

Authors:  S Ter-Avetisyan; M Schnürer; P V Nickles; M Kalashnikov; E Risse; T Sokollik; W Sandner; A Andreev; V Tikhonchuk
Journal:  Phys Rev Lett       Date:  2006-04-14       Impact factor: 9.161

8.  Effect of target composition on proton energy spectra in ultraintense laser-solid interactions.

Authors:  A P L Robinson; A R Bell; R J Kingham
Journal:  Phys Rev Lett       Date:  2006-01-27       Impact factor: 9.161

9.  High-energy ions from near-critical density plasmas via magnetic vortex acceleration.

Authors:  Tatsufumi Nakamura; Sergei V Bulanov; Timur Zh Esirkepov; Masaki Kando
Journal:  Phys Rev Lett       Date:  2010-09-23       Impact factor: 9.161

10.  Laser-driven proton acceleration enhancement by nanostructured foils.

Authors:  D Margarone; O Klimo; I J Kim; J Prokůpek; J Limpouch; T M Jeong; T Mocek; J Pšikal; H T Kim; J Proška; K H Nam; L Stolcová; I W Choi; S K Lee; J H Sung; T J Yu; G Korn
Journal:  Phys Rev Lett       Date:  2012-12-03       Impact factor: 9.161

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