Literature DB >> 24155427

Cantharidin toxicosis in 2 alpacas.

Katharine M Simpson1, Robert N Streeter, Patricia De Souza, Suzanne G Genova, Sandra E Morgan.   

Abstract

Two adult alpacas were presented for recumbency and reluctance to rise. Cantharidin toxicosis was suspected based on clinical and ancillary diagnostic findings. The diagnosis was confirmed by gas chromatography-mass spectrometry of gastric contents and urine. Despite medical treatment, neither alpaca survived. Blister beetle toxicosis has not been previously described in camelids. Challenges in treatment of affected ruminants or pseudoruminants are noted.

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Year:  2013        PMID： 24155427      PMCID： PMC3624911     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  24 in total

1.  Inhibitory effect of cantharidin on osteoclast differentiation and bone resorption.

Authors:  Myung Hee Kim; Ki Shuk Shim; Seong Hwan Kim
Journal:  Arch Pharm Res       Date:  2010-03-30       Impact factor: 4.946

2.  GC/MS confirmation of cantharidin toxicosis due to ingestion of blister beetles.

Authors:  A C Ray; L O Post; J C Reagor
Journal:  Vet Hum Toxicol       Date:  1980-12

3.  Evaluation of an analytical method for the diagnosis of cantharidin toxicosis due to ingestion of blister beetles (Epicauta lemniscata) by horses and sheep.

Authors:  A C Ray; L O Post; J M Hurst; W C Edwards; J C Reagor
Journal:  Am J Vet Res       Date:  1980-06       Impact factor: 1.156

4.  The mechanism of action of cantharidin in smooth muscle.

Authors:  J Knapp; P Bokník; S Huke; H Lüss; F U Müller; T Müller; P Nacke; W Schmitz; U Vahlensieck; J Neumann
Journal:  Br J Pharmacol       Date:  1998-03       Impact factor: 8.739

5.  Cantharidin-binding protein: identification as protein phosphatase 2A.

Authors:  Y M Li; J E Casida
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

6.  Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A.

Authors:  R E Honkanen
Journal:  FEBS Lett       Date:  1993-09-20       Impact factor: 4.124

7.  Experimental cantharidiasis in the horse.

Authors:  R V Shawley; L L Rolf
Journal:  Am J Vet Res       Date:  1984-11       Impact factor: 1.156

8.  Post-mortem serum concentration of cantharidin in a fatal case of cantharides poisoning.

Authors:  H K Hundt; J M Steyn; L Wagner
Journal:  Hum Exp Toxicol       Date:  1990-01       Impact factor: 2.903

9.  Effects of serine/threonine protein phosphatase inhibitors on morphine-induced antinociception in the tail flick test in mice.

Authors:  Ana Moncada; Cruz Miguel Cendán; José M Baeyens; Esperanza Del Pozo
Journal:  Eur J Pharmacol       Date:  2003-03-28       Impact factor: 4.432

10.  Protein phosphatase 2A and its [3H]cantharidin/[3H]endothall thioanhydride binding site. Inhibitor specificity of cantharidin and ATP analogues.

Authors:  Y M Li; C Mackintosh; J E Casida
Journal:  Biochem Pharmacol       Date:  1993-10-19       Impact factor: 5.858
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  1 in total

1.  Entomological Surveillance and Cantharidin Concentrations in Mylabris variabilis and Epicauta rufidorsum Blister Beetles in Slovenia.

Authors:  Breda Jakovac-Strajn; Diana Brozić; Gabrijela Tavčar-Kalcher; Janja Babič; Tomi Trilar; Modest Vengust
Journal:  Animals (Basel)       Date:  2021-01-18       Impact factor: 2.752
  1 in total

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