Literature DB >> 24155230

An assay to quantify chemotactic properties of degradation products from extracellular matrix.

Brian M Sicari1, Li Zhang, Ricardo Londono, Stephen F Badylak.   

Abstract

The endogenous chemotaxis of cells toward sites of tissue injury and/or biomaterial implantation is an important component of the host response. Implanted biomaterials capable of recruiting host stem/progenitor cells to a site of interest may obviate challenges associated with cell transplantation. An assay for the identification and quantification of chemotaxis induced by surgically placed biologic scaffolds composed of extracellular matrix is described herein.

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Year:  2014        PMID： 24155230      PMCID： PMC4317790          DOI： 10.1007/7651_2013_37

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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