Literature DB >> 24153132

Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic Clostridium difficile in asymptomatic carriers.

Curtis J Donskey1, Venkata C K Sunkesula, Annette L Jencson, Nimalie D Stone, Carolyn V Gould, L Clifford McDonald, Matthew Samore, Jeanmarie Mayer, Susan Pacheco, Susan Sambol, Laurica Petrella, Deborah Terry, Dale N Gerding.   

Abstract

A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile, including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.

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Year:  2013        PMID： 24153132      PMCID： PMC3911416          DOI： 10.1128/JCM.01852-13

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  14 in total

1.  Perirectal swab surveillance for Clostridium difficile by use of selective broth preamplification and real-time PCR detection of tcdB.

Authors:  Scott R Curry; Jessica L Schlackman; Travis M Hamilton; Tatianna K Henderson; Nakita T Brown; Jane W Marsh; Kathleen A Shutt; Maria M Brooks; A William Pasculle; Carlene A Muto; Lee H Harrison
Journal:  J Clin Microbiol       Date:  2011-08-31       Impact factor: 5.948

2.  Is Clostridium difficile endemic in chronic-care facilities?

Authors:  B S Bender; R Bennett; B E Laughon; W B Greenough; C Gaydos; S D Sears; M S Forman; J G Bartlett
Journal:  Lancet       Date:  1986-07-05       Impact factor: 79.321

3.  Host and pathogen factors for Clostridium difficile infection and colonization.

Authors:  Vivian G Loo; Anne-Marie Bourgault; Louise Poirier; François Lamothe; Sophie Michaud; Nathalie Turgeon; Baldwin Toye; Axelle Beaudoin; Eric H Frost; Rodica Gilca; Paul Brassard; Nandini Dendukuri; Claire Béliveau; Matthew Oughton; Ivan Brukner; Andre Dascal
Journal:  N Engl J Med       Date:  2011-11-03       Impact factor: 91.245

4.  Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA).

Authors:  Stuart H Cohen; Dale N Gerding; Stuart Johnson; Ciaran P Kelly; Vivian G Loo; L Clifford McDonald; Jacques Pepin; Mark H Wilcox
Journal:  Infect Control Hosp Epidemiol       Date:  2010-05       Impact factor: 3.254

5.  Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents.

Authors:  Michelle M Riggs; Ajay K Sethi; Trina F Zabarsky; Elizabeth C Eckstein; Robin L P Jump; Curtis J Donskey
Journal:  Clin Infect Dis       Date:  2007-09-04       Impact factor: 9.079

6.  Clostridium difficile colonization in residents of long-term care facilities: prevalence and risk factors.

Authors:  K J Walker; S S Gilliland; K Vance-Bryan; J A Moody; A J Larsson; J C Rotschafer; D R Guay
Journal:  J Am Geriatr Soc       Date:  1993-09       Impact factor: 5.562

7.  Utility of perirectal swab specimens for diagnosis of Clostridium difficile infection.

Authors:  Sirisha Kundrapu; Venkata C K Sunkesula; Lucy A Jury; Ajay K Sethi; Curtis J Donskey
Journal:  Clin Infect Dis       Date:  2012-08-21       Impact factor: 9.079

8.  Acquisition of Clostridium difficile by hospitalized patients: evidence for colonized new admissions as a source of infection.

Authors:  C R Clabots; S Johnson; M M Olson; L R Peterson; D N Gerding
Journal:  J Infect Dis       Date:  1992-09       Impact factor: 5.226

9.  Postantibiotic colonization with Clostridium difficile in nursing home patients.

Authors:  D R Thomas; R G Bennett; B E Laughon; W B Greenough; J G Bartlett
Journal:  J Am Geriatr Soc       Date:  1990-04       Impact factor: 5.562

10.  Infection due to Clostridium difficile among elderly residents of a long-term-care facility.

Authors:  A E Simor; S L Yake; K Tsimidis
Journal:  Clin Infect Dis       Date:  1993-10       Impact factor: 9.079
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  9 in total

1.  Diagnosing an Infection Control Risk.

Authors:  Preeta K Kutty; L Clifford McDonald
Journal:  Clin Infect Dis       Date:  2017-05-01       Impact factor: 9.079

2.  Intestinal microbiome disruption in patients in a long-term acute care hospital: A case for development of microbiome disruption indices to improve infection prevention.

Authors:  Alison Laufer Halpin; Tom J B de Man; Colleen S Kraft; K Allison Perry; Austin W Chan; Sung Lieu; Jeffrey Mikell; Brandi M Limbago; L Clifford McDonald
Journal:  Am J Infect Control       Date:  2016-02-19       Impact factor: 2.918

3.  Point-Counterpoint: Active Surveillance for Carriers of Toxigenic Clostridium difficile Should Be Performed To Guide Prevention Efforts.

Authors:  L Clifford McDonald; Daniel J Diekema
Journal:  J Clin Microbiol       Date:  2018-07-26       Impact factor: 5.948

4.  Recombinant antigens rLipL21, rLoa22, rLipL32 and rLigACon4-8 for serological diagnosis of leptospirosis by enzyme-linked immunosorbent assays in dogs.

Authors:  Cuilian Ye; Weiwei Yan; Hua Xiang; Hongxuan He; Maosheng Yang; Muhammad Ijaz; Nicodemus Useh; Ching-Lin Hsieh; Patrick L McDonough; Sean P McDonough; Hussni Mohamed; Zhibang Yang; Yung-Fu Chang
Journal:  PLoS One       Date:  2014-12-19       Impact factor: 3.240

5.  C. difficile Infection: Changing Epidemiology and Management Paradigms.

Authors:  Stephen M Vindigni; Christina M Surawicz
Journal:  Clin Transl Gastroenterol       Date:  2015-07-09       Impact factor: 4.488

6.  Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients.

Authors:  Klaus Nissle; Daniel Kopf; Alexander Rösler
Journal:  BMC Geriatr       Date:  2016-11-15       Impact factor: 3.921

7.  Low frequency of asymptomatic carriage of toxigenic Clostridium difficile in an acute care geriatric hospital: prospective cohort study in Switzerland.

Authors:  Daniela Pires; Virginie Prendki; Gesuele Renzi; Carolina Fankhauser; Valerie Sauvan; Benedikt Huttner; Jacques Schrenzel; Stephan Harbarth
Journal:  Antimicrob Resist Infect Control       Date:  2016-06-08       Impact factor: 4.887

8.  Colonization of toxigenic Clostridium difficile among ICU patients: a prospective study.

Authors:  Xiaoxia Zhang; Xiaohui Wang; Jingyu Yang; Xiaohua Liu; Lin Cai; Zhiyong Zong
Journal:  BMC Infect Dis       Date:  2016-08-09       Impact factor: 3.090

9.  Unique Clindamycin-Resistant Clostridioides difficile Strain Related to Fluoroquinolone-Resistant Epidemic BI/RT027 Strain.

Authors:  Andrew M Skinner; Laurica Petrella; Farida Siddiqui; Susan P Sambol; Christopher A Gulvik; Dale N Gerding; Curtis J Donskey; Stuart Johnson
Journal:  Emerg Infect Dis       Date:  2020-02       Impact factor: 6.883
  9 in total

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