Literature DB >> 2415267

Serum alpha fetoprotein kinetics in hepatocellular carcinoma. A case for cessation of therapy.

P K Buamah, A W Skillen, A M Ward.   

Abstract

As chemotherapy with adriamycin is accompanied by toxic side effects, early recognition of ineffective treatment is important. Marker kinetics, apparent half-life (AFL) and doubling time (DT), showed that in five patients with advanced hepatocellular carcinoma, adriamycin was ineffective. Failure of the chemotherapeutic regimen was apparent by the third course of treatment.

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Year:  1986        PMID: 2415267     DOI: 10.1007/bf00255291

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN: 0344-5704            Impact factor:   3.333


  7 in total

1.  Serum alpha-fetoprotein and resection of primary hepatic cancer.

Authors:  K Sugahara; A Kashii; H Kogure; J Manaka; T Shirakura; S Mitani
Journal:  Arch Surg       Date:  1973-01

2.  Serum alpha-fetoprotein, albumin, and gamma-G-globulin in the human conceptus.

Authors:  D Gitlin; M Boesman
Journal:  J Clin Invest       Date:  1966-11       Impact factor: 14.808

3.  Synthesis of -fetoprotein by liver, yolk sac, and gastrointestinal tract of the human conceptus.

Authors:  D Gitlin; A Perricelli; G M Gitlin
Journal:  Cancer Res       Date:  1972-05       Impact factor: 12.701

4.  Serial monitoring of serum alpha-fetoprotein and chorionic gonadotropin in males with germ cell tumors.

Authors:  D K Thompson; J E Haddow
Journal:  Cancer       Date:  1979-05       Impact factor: 6.860

5.  Alpha fetoprotein in embryonal hepatoblastoma.

Authors:  M E Alpert; R A Seeler
Journal:  J Pediatr       Date:  1970-12       Impact factor: 4.406

6.  Alpha-fetoprotein and germ cell tumors: a possible role of yolk sac tumor in production of alpha-fetoprotein.

Authors:  A Talerman; W G Haije
Journal:  Cancer       Date:  1974-11       Impact factor: 6.860

7.  Evaluation of alpha-fetoprotein in early infancy.

Authors:  Y Tsuchida; Y Endo; S Saito; M Kaneko; K Shiraki; K Ohmi
Journal:  J Pediatr Surg       Date:  1978-04       Impact factor: 2.545

  7 in total

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