Literature DB >> 24152568

Triterpenoid saponins from the roots of Clematis uncinata.

Shuo-Guo Li1, Xiao-Jun Huang, Man-Mei Li, Mei Wang, Rui-Bing Feng, Wei Zhang, Yao-Lan Li, Ying Wang, Wen-Cai Ye.   

Abstract

Eight new bisdesmosidic triterpenoid saponins, clematiunicinosides A-H (1-8), along with eleven known ones (9-19), were isolated from the roots of Clematis uncinata. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All the isolated saponins were tested for their cytotoxic activities on human caski cervical cancer (Caski) cells, and compounds 13, 17 and 19 exhibited inhibitory effect on Caski cells.

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Year:  2013        PMID: 24152568     DOI: 10.1248/cpb.c13-00269

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  2 in total

1.  Cytotoxic Activities of Total Saponins from Plena Clematis on Human Tumor Cell Lines In Vitro.

Authors:  Fu-Rong Zhu; Yong-Ning Li; Shu-Lan He; Qian-Shun Chen; Xun-Yu Xu
Journal:  Chin J Integr Med       Date:  2018-06-21       Impact factor: 1.978

Review 2.  Anticancer Chemodiversity of Ranunculaceae Medicinal Plants: Molecular Mechanisms and Functions.

Authors:  Da-Cheng Hao; Chun-Nian He; Jie Shen; Pei-Gen Xiao
Journal:  Curr Genomics       Date:  2017-02       Impact factor: 2.236

  2 in total

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