Literature DB >> 24152046

Withanolide artifacts formed in methanol.

Cong-Mei Cao1, Huaping Zhang, Robert J Gallagher, Barbara N Timmermann.   

Abstract

Methanol solutions of the main withanolides (6-8) naturally present in Physalis longifolia yielded five artificial withanolides (1-5), including three new compounds (1-3). Withanolides 1 and 2 were identified as intramolecular Michael addition derivatives, while withanolides 3-5 were the result of intermolecular Michael addition. A comprehensive literature investigation was conducted to identify potential withanolide Michael addition artifacts isolated from Solanaceous species to date.

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Year:  2013        PMID： 24152046     DOI： 10.1021/np400296s

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Stereo- and region-specific biotransformation of physapubescin by four fungal strains.

Authors:  Chongyue Qiu; Ting Yuan; Dejuan Sun; Suyu Gao; Lixia Chen
Journal:  J Nat Med       Date:  2017-01-10       Impact factor: 2.343

2.  Analysis of Major Withanolides in Physalis longifolia Nutt. by HPLC-PDA.

Authors:  Cong-Mei Cao; Kelly Kindscher; Robert J Gallagher; Huaping Zhang; Barbara N Timmermann
Journal:  J Chromatogr Sci       Date:  2014-12-02       Impact factor: 1.618

3.  New withanolides from Physalis minima and their cytotoxicity against A375 human melanoma cells.

Authors:  Meng Zhang; Bingyang Zhang; Chenxi Guang; Benke Jiang; Xinya He; Shijie Cao; Liqin Ding; Ning Kang; Lixia Chen; Feng Qiu
Journal:  RSC Adv       Date:  2020-06-16       Impact factor: 4.036

4.  Prealamethicin F50 and related peptaibols from Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis.

Authors:  José Rivera-Chávez; Huzefa A Raja; Tyler N Graf; Jacklyn M Gallagher; Prashant Metri; Ding Xue; Cedric J Pearce; Nicholas H Oberlies
Journal:  RSC Adv       Date:  2017-09-25       Impact factor: 3.361

Review 5.  Antiproliferative withanolides from several solanaceous species.

Authors:  Huaping Zhang; Cong-Mei Cao; Robert J Gallagher; Barbara N Timmermann
Journal:  Nat Prod Res       Date:  2014-05-28       Impact factor: 2.861

6.  Silica Gel-mediated Oxidation of Prenyl Motifs Generates Natural Product-Like Artifacts.

Authors:  Yu Tang; J Brent Friesen; Dejan S Nikolić; David C Lankin; James B McAlpine; Shao-Nong Chen; Guido F Pauli
Journal:  Planta Med       Date:  2021-05-11       Impact factor: 3.007
  6 in total

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