Literature DB >> 2415156

Thyroid hormone regulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat liver.

D S Loose, D K Cameron, H P Short, R W Hanson.   

Abstract

Using an in vitro assay with isolated rat nuclei, we have determined that thyroid hormone causes a 4-6-fold increase in the synthesis of mRNA coding for phosphoenolpyruvate carboxykinase. Proportional changes were seen in the steady-state cytosolic mRNA levels for phosphoenolpyruvate carboxykinase. Dibutyryladenosine cyclic 3',5'-monophosphate, which stimulates transcription of the phosphoenolpyruvate carboxykinase gene in normal rats, remained effective in hypo- or hyperthyroid animals. The effect of epinephrine on transcription of the gene for phosphoenolpyruvate carboxykinase appears to be modulated by thyroid hormone.

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Year:  1985        PMID： 2415156     DOI： 10.1021/bi00338a004

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


  23 in total

1.  Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice.

Authors:  M K Short; D E Clouthier; I M Schaefer; R E Hammer; M A Magnuson; E G Beale
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2.  Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1.

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3.  Similarities and differences between two modes of antagonism of the thyroid hormone receptor.

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Journal:  ACS Chem Biol       Date:  2011-08-15       Impact factor: 5.100

Review 4.  Thyroid hormones and the metabolic syndrome.

Authors:  K Alexander Iwen; Erich Schröder; Georg Brabant
Journal:  Eur Thyroid J       Date:  2013-05-28

5.  Glucocorticoids control phosphoenolpyruvate carboxykinase gene expression in a tissue specific manner.

Authors:  H Nechushtan; N Benvenisty; R Brandeis; L Reshef
Journal:  Nucleic Acids Res       Date:  1987-08-25       Impact factor: 16.971

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Authors:  S Markowitz; M Haut; T Stellato; C Gerbic; K Molkentin
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7.  Developmental regulation of hepatic and renal gluconeogenic enzymes by thyroid hormones in fetal sheep during late gestation.

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8.  Transcriptional regulation of liver phosphoenolpyruvate carboxykinase by biotin in diabetic rats.

Authors:  K Dakshinamurti; W Li
Journal:  Mol Cell Biochem       Date:  1994-03-30       Impact factor: 3.396

9.  A TRbeta-selective agonist confers resistance to diet-induced obesity.

Authors:  Beatriz S Amorim; Cintia B Ueta; Beatriz C G Freitas; Renata J Nassif; Cecília Helena de Azevedo Gouveia; Marcelo A Christoffolete; Anselmo S Moriscot; Carmen Lucia Lancelloti; Flávia Llimona; Hermes Vieira Barbeiro; Heraldo Possolo de Souza; Sergio Catanozi; Marisa Passarelli; Marcelo S Aoki; Antonio C Bianco; Miriam O Ribeiro
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10.  Specificity of a retinoic acid response element in the phosphoenolpyruvate carboxykinase gene promoter: consequences of both retinoic acid and thyroid hormone receptor binding.

Authors:  P C Lucas; B M Forman; H H Samuels; D K Granner
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272
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