Literature DB >> 2415129

Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes.

D A Bernlohr, T L Doering, T J Kelly, M D Lane.   

Abstract

The differentiation of 3T3-L1 preadipocytes leads to the expression of a new protein, p422, and its mRNA. This protein has 70% and 20-30% amino acid sequence homology to myelin P2 and the fatty acid binding proteins of liver and intestine, respectively. Investigation of the distribution in mouse tissues of p422 protein by immunoblotting and of p422 mRNA by cDNA hybridization indicates that they are expressed only in adipose tissue. Liver and intestinal fatty acid binding protein mRNA's were not detectable in mouse adipose tissue or in 3T3-L1 adipocytes. It is suggested that p422 functions as an adipocyte fatty acid binding protein.

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Year:  1985        PMID： 2415129     DOI： 10.1016/0006-291x(85)91209-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  25 in total

1.  Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.

Authors:  R A Graves; P Tontonoz; B M Spiegelman
Journal:  Mol Cell Biol       Date:  1992-03       Impact factor: 4.272

2.  A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.

Authors:  S R Ross; R A Graves; A Greenstein; K A Platt; H L Shyu; B Mellovitz; B M Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

3.  Identification of phosphorylated 422(aP2) protein as pp15, the 15-kilodalton target of the insulin receptor tyrosine kinase in 3T3-L1 adipocytes.

Authors:  R C Hresko; M Bernier; R D Hoffman; J R Flores-Riveros; K Liao; D M Laird; M D Lane
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

Review 4.  Functions of fatty acid binding proteins.

Authors:  R M Kaikaus; N M Bass; R K Ockner
Journal:  Experientia       Date:  1990-06-15

5.  Human adipose tissue is a source of multipotent stem cells.

Authors:  Patricia A Zuk; Min Zhu; Peter Ashjian; Daniel A De Ugarte; Jerry I Huang; Hiroshi Mizuno; Zeni C Alfonso; John K Fraser; Prosper Benhaim; Marc H Hedrick
Journal:  Mol Biol Cell       Date:  2002-12       Impact factor: 4.138

Review 6.  Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?

Authors:  S Kralisch; M Fasshauer
Journal:  Diabetologia       Date:  2012-09-29       Impact factor: 10.122

7.  Increase in membrane uptake of long-chain fatty acids early during preadipocyte differentiation.

Authors:  N A Abumrad; C C Forest; D M Regen; S Sanders
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

8.  Biochemical and biophysical analysis of the intracellular lipid binding proteins of adipocytes.

Authors:  M A Simpson; V J LiCata; N Ribarik Coe; D A Bernlohr
Journal:  Mol Cell Biochem       Date:  1999-02       Impact factor: 3.396

9.  Growth hormone regulation of the expression of differentiation-dependent genes in preadipocyte Ob1771 cells.

Authors:  A Doglio; C Dani; P Grimaldi; G Ailhaud
Journal:  Biochem J       Date:  1986-08-15       Impact factor: 3.857

10.  Life without white fat: a transgenic mouse.

Authors:  J Moitra; M M Mason; M Olive; D Krylov; O Gavrilova; B Marcus-Samuels; L Feigenbaum; E Lee; T Aoyama; M Eckhaus; M L Reitman; C Vinson
Journal:  Genes Dev       Date:  1998-10-15       Impact factor: 11.361
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