Literature DB >> 2415125

Expression of c-myc gene in human hepatoma.

T S Su, L H Lin, W Y Lui, C M Chang, C K Chou, L P Ting, C P Hu, S H Han, F K P'eng.   

Abstract

The level of c-myc transcript was examined in liver samples from seven hepatoma patients. Transcripts were detected in all the normal liver parts examined; in contrast, in two hepatoma parts, there was a dramatic reduction in c-myc transcripts. The restriction enzyme pattern of c-myc gene appeared the same among samples. The data suggest that c-myc gene expression might not be required for the maintenance of the tumor state in human liver carcinogenesis.

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Year:  1985        PMID: 2415125     DOI: 10.1016/0006-291x(85)91017-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  4 in total

1.  Expression of p53 and C-myc genes and its clinical relevance in the hepatocellular carcinomatous and pericarcinomatous tissues.

Authors:  Zhao-Shan Niu; Bo-Kian Li; Mei Wang
Journal:  World J Gastroenterol       Date:  2002-10       Impact factor: 5.742

2.  Hypomethylation of the c-myc oncogene in liver cirrhosis and chronic hepatitis.

Authors:  N Aiba; S Nambu; K Inoue; H Sasaki
Journal:  Gastroenterol Jpn       Date:  1989-06

3.  Molecular mechanisms underlying hepatocellular carcinoma.

Authors:  Philippe Merle; Christian Trepo
Journal:  Viruses       Date:  2009-11-09       Impact factor: 5.048

4.  Expression of oncogenes during rat chemical hepatotumorigenesis promoted by estrogen.

Authors:  Y Himeno; Y Fukuda; M Hatanaka; H Imura
Journal:  Jpn J Cancer Res       Date:  1989-08
  4 in total

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