Literature DB >> 24150599

Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1.

Zhaoyong Xi1, Wei Guo, Changlin Tian, Fuyi Wang, Yangzhong Liu.   

Abstract

Cu(I) binding promotes the platination of Atox1, although cisplatin binds to the copper coordination sites. In addition, Cu(I) binding enhances the competition of Atox1 with DTT in the reaction of cisplatin. These results indicate that cuprous ions could regulate the cellular trafficking of cisplatin.

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Year:  2013        PMID： 24150599     DOI： 10.1039/c3cc45905e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Copper transporters and chaperones CTR1, CTR2, ATOX1, and CCS as determinants of cisplatin sensitivity.

Authors:  Kristin M Bompiani; Cheng-Yu Tsai; Felix P Achatz; Janika K Liebig; Stephen B Howell
Journal:  Metallomics       Date:  2016-05-09       Impact factor: 4.526

2.  Cisplatin handover between copper transporters: the effect of reducing agents.

Authors:  Angela Galliani; Maurizio Losacco; Alessia Lasorsa; Giovanni Natile; Fabio Arnesano
Journal:  J Biol Inorg Chem       Date:  2014-05-01       Impact factor: 3.358

3.  An unexpected all-metal aromatic tetranuclear silver cluster in human copper chaperone Atox1.

Authors:  Xiuxiu Wang; Zong-Chang Han; Wei Wei; Hanshi Hu; Pengfei Li; Peiqing Sun; Xiangzhi Liu; Zhijia Lv; Feng Wang; Yi Cao; Zijian Guo; Jun Li; Jing Zhao
Journal:  Chem Sci       Date:  2022-05-30       Impact factor: 9.969

4.  The Effect of Salts in Promoting Specific and Competitive Interactions between Zinc Finger Proteins and Metals.

Authors:  Gongyu Li; Siming Yuan; Shihui Zheng; Yuting Chen; Zhen Zheng; Yangzhong Liu; Guangming Huang
Journal:  J Am Soc Mass Spectrom       Date:  2017-09-08       Impact factor: 3.109

5.  JP3 enhances the toxicity of cisplatin on drug-resistant gastric cancer cells while reducing the damage to normal cells.

Authors:  Yi Zhang; Junjie Chen; Zhen Che; Chuanjun Shu; Dongyin Chen; Kun Ding; Aiping Li; Jianwei Zhou
Journal:  J Cancer       Date:  2021-01-30       Impact factor: 4.207

6.  Cisplatin inhibits MEK1/2.

Authors:  Tetsu Yamamoto; Igor F Tsigelny; Andreas W Götz; Stephen B Howell
Journal:  Oncotarget       Date:  2015-09-15

Review 7.  Modulating Chemosensitivity of Tumors to Platinum-Based Antitumor Drugs by Transcriptional Regulation of Copper Homeostasis.

Authors:  Yu-Hsuan Lai; Chin Kuo; Macus Tien Kuo; Helen H W Chen
Journal:  Int J Mol Sci       Date:  2018-05-16       Impact factor: 5.923

8.  Oxidation of Human Copper Chaperone Atox1 and Disulfide Bond Cleavage by Cisplatin and Glutathione.

Authors:  Maria I Nardella; Antonio Rosato; Benny D Belviso; Rocco Caliandro; Giovanni Natile; Fabio Arnesano
Journal:  Int J Mol Sci       Date:  2019-09-06       Impact factor: 5.923
  8 in total

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