Literature DB >> 24150387

Snapshot molecular imaging using coded energy-sensitive detection.

Joel A Greenberg, Kalyani Krishnamurthy, David Brady.   

Abstract

We demonstrate a technique for measuring the range-resolved coherent scatter form factors of different objects from a single snapshot. By illuminating the object with an x-ray pencil beam and placing a coded aperture in front of a linear array of energy-sensitive detector elements, we record the coherently scattered x-rays. This approach yields lateral, range, and momentum transfer resolutions of 1 mm, 5 mm, and 0.2 nm⁻¹, respectively, which is sufficient for the distinguishing a variety of solids and liquids. These results indicate a path toward real-time volumetric molecular imaging for non-destructive examination in a variety of applications, including medical diagnostics, quality inspection, and security detection.

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Year:  2013        PMID: 24150387     DOI: 10.1364/OE.21.025480

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  5 in total

1.  Two-dimensional aperture coding for magnetic sector mass spectrometry.

Authors:  Zachary E Russell; Evan X Chen; Jason J Amsden; Scott D Wolter; Ryan M Danell; Charles B Parker; Brian R Stoner; Michael E Gehm; David J Brady; Jeffrey T Glass
Journal:  J Am Soc Mass Spectrom       Date:  2014-12-16       Impact factor: 3.109

2.  Accuracy assessment and characterization of x-ray coded aperture coherent scatter spectral imaging for breast cancer classification.

Authors:  Manu N Lakshmanan; Joel A Greenberg; Ehsan Samei; Anuj J Kapadia
Journal:  J Med Imaging (Bellingham)       Date:  2017-03-07

3.  Design and implementation of coded aperture coherent scatter spectral imaging of cancerous and healthy breast tissue samples.

Authors:  Manu N Lakshmanan; Joel A Greenberg; Ehsan Samei; Anuj J Kapadia
Journal:  J Med Imaging (Bellingham)       Date:  2016-02-16

4.  Application of machine learning classifiers to X-ray diffraction imaging with medically relevant phantoms.

Authors:  Stefan Stryker; Anuj J Kapadia; Joel A Greenberg
Journal:  Med Phys       Date:  2021-12-01       Impact factor: 4.071

5.  X-ray fan beam coded aperture transmission and diffraction imaging for fast material analysis.

Authors:  Stefan Stryker; Joel A Greenberg; Shannon J McCall; Anuj J Kapadia
Journal:  Sci Rep       Date:  2021-05-19       Impact factor: 4.379

  5 in total

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