| Literature DB >> 24149619 |
Jun Yi1, Guan Ye, Leonard M Thomas, George B Richter-Addo.
Abstract
The crystal structure of the nitrosomethane adduct of human Hb shows N-binding of the MeNO ligands to heme Fe. The structure of the EtNO adduct reveals a surprising 4.9 Å heme slippage in the β subunit, and explains the ability of C-nitroso compounds to degrade Hb removing it from circulation.Entities:
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Year: 2013 PMID： 24149619 DOI： 10.1039/c3cc46174b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222