Literature DB >> 24149613

Exercise limitations in a competitive cyclist twelve months post heart transplantation.

Jeremy A Patterson1, Nicolas G Walton.   

Abstract

It has been well documented that for heart transplant recipients (HTrecipient) post transplantation exercise capacity does not exceed 60% of healthy age-matched controls. Few studies have been undertaken to determine the cause of exercise limitations following heart transplantation (HT) for an elite athlete. Participant was a 39 year old elite male cyclist who suffered an acute myocardial infarction after a cycling race and received a heart transplant (HT) four months later. Six weeks prior to his AMI fitness testing was completed and a predicted VO2max of 58 mL·kg(-1)·min(-1) and HRmax of 171 bpm was achieved. The participant underwent maximal exercise testing 6 and 12 months post transplant to determine exercise limitations. His results 6 and 12 months post transplant were a VO2max of 33.8 and 44.2 mL·kg(-1)·min(-1) respectively, and a HR max that was 97% and 96% of HRmax measured. The participant showed an increase in both HRmax and VO2max 12 months post HT compared to previous testing. Results suggest that the limiting factors to exercise following HT are likely due to peripheral function, which became diminished as a result accumulated from 4 months of congestive heart failure, the strain of HT, and immunosuppressive therapy leading up to the exercise testing. Lifestyle before HT and a more aggressive approach to HT recovery should be considered necessary in the improvement of peripheral functioning following HT. Key pointsPhysical work capacity following heart transplantation is not limited by cardiac denervation.Heart transplant rehabilitation should focus efforts on endothelial and muscular limitations.

Entities:  

Keywords:  Transplant rehabilitation; aerobic capacity; orthotopic transplant

Year:  2009        PMID: 24149613      PMCID: PMC3761552     

Source DB:  PubMed          Journal:  J Sports Sci Med        ISSN: 1303-2968            Impact factor:   2.988


  42 in total

1.  Attenuated responses of Doppler-derived hemodynamic parameters during supine bicycle exercise in heart transplant recipients.

Authors:  I Auerbach; A Tenenbaum; M Motro; C I Stroh; Y Har-Zahav; E Z Fisman
Journal:  Cardiology       Date:  1999       Impact factor: 1.869

2.  Effect of sympathetic reinnervation on cardiac performance after heart transplantation.

Authors:  F M Bengel; P Ueberfuhr; N Schiepel; S G Nekolla; B Reichart; M Schwaiger
Journal:  N Engl J Med       Date:  2001-09-06       Impact factor: 91.245

3.  Effects of upper extremity exercise training on peak aerobic and anaerobic fitness in patients after transplantation.

Authors:  Darren E R Warburton; A William Sheel; Alastair N H Hodges; Ian B Stewart; Eric M Yoshida; Robert D Levy; Donald C McKenzie
Journal:  Am J Cardiol       Date:  2004-04-01       Impact factor: 2.778

4.  Serial assessment of sympathetic reinnervation after orthotopic heart transplantation. A longitudinal study using PET and C-11 hydroxyephedrine.

Authors:  F M Bengel; P Ueberfuhr; S I Ziegler; S Nekolla; B Reichart; M Schwaiger
Journal:  Circulation       Date:  1999-04-13       Impact factor: 29.690

5.  Basis for aerobic impairment in patients after heart transplantation.

Authors:  L M Bussières; P W Pflugfelder; A H Menkis; R J Novick; F N McKenzie; A W Taylor; W J Kostuk
Journal:  J Heart Lung Transplant       Date:  1995 Nov-Dec       Impact factor: 10.247

Review 6.  Exercise and heart transplantation. A review.

Authors:  G Niset; L Hermans; P Depelchin
Journal:  Sports Med       Date:  1991-12       Impact factor: 11.136

7.  Case report on PWC of a competitive cyclist before and after heart transplant.

Authors:  Jeremy A Patterson; Kenneth H Pitetti; Kaelin C Young; William F Goodman; Hussam Farhoud
Journal:  Med Sci Sports Exerc       Date:  2007-09       Impact factor: 5.411

8.  Endothelium-dependent vasodilation of the skin microcirculation in heart transplant recipients.

Authors:  A K Andreassen; L Gullestad; T Holm; S Simonsen; K Kvernebo
Journal:  Clin Transplant       Date:  1998-08       Impact factor: 2.863

9.  Circuit resistance training in chronic heart failure improves skeletal muscle mitochondrial ATP production rate--a randomized controlled trial.

Authors:  Andrew D Williams; Michael F Carey; Steve Selig; Alan Hayes; Henry Krum; Jeremy Patterson; Deidre Toia; David L Hare
Journal:  J Card Fail       Date:  2007-03       Impact factor: 5.712

10.  A controlled trial of exercise rehabilitation after heart transplantation.

Authors:  J A Kobashigawa; D A Leaf; N Lee; M P Gleeson; H Liu; M A Hamilton; J D Moriguchi; N Kawata; K Einhorn; E Herlihy; H Laks
Journal:  N Engl J Med       Date:  1999-01-28       Impact factor: 91.245

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.