Literature DB >> 2414918

Identification and antigenicity of the major envelope glycoprotein of lymphadenopathy-associated virus.

L Montagnier, F Clavel, B Krust, S Chamaret, F Rey, F Barré-Sinoussi, J C Chermann.   

Abstract

The major envelope glycoprotein of the causative agent of Acquired Immune Deficiency Syndrome (AIDS) lymphadenopathy-associated virus (LAV) has been identified and characterized. The glycoprotein has an apparent molecular weight of 110,000-120,000 under denaturing conditions in polyacrylamide gel electrophoresis. Upon deglycosylation by a specific endoglycosydase, its size is reduced to 80,000. Cellular precursors of this glycoprotein have been detected with apparent molecular weight of 150,000 and 135,000. Nearly all AIDS and pre-AIDS patients have detectable antibodies against this viral glycoprotein.

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Year:  1985        PMID： 2414918     DOI： 10.1016/0042-6822(85)90326-5

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  37 in total

1.  Monoclonal antibodies to gp110 and gp41 of human immunodeficiency virus.

Authors:  L H Gosting; J McClure; E S Dickinson; S M Watanabe; K Shriver; L C Goldstein
Journal:  J Clin Microbiol       Date:  1987-05       Impact factor: 5.948

2.  Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses.

Authors:  P L Earl; S Koenig; B Moss
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

3.  Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41.

Authors:  E O Freed; D J Myers; R Risser
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

4.  Expression of the human immunodeficiency virus envelope glycoprotein is restricted to basolateral surfaces of polarized epithelial cells.

Authors:  R J Owens; R W Compans
Journal:  J Virol       Date:  1989-02       Impact factor: 5.103

5.  Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1.

Authors:  A Pinter; W J Honnen; S A Tilley; C Bona; H Zaghouani; M K Gorny; S Zolla-Pazner
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

6.  Production and characterization of monoclonal antibodies specific for the transmembrane protein of simian immunodeficiency virus from the African green monkey.

Authors:  T Kodama; Y Ohta; T Masuda; K Ishikawa; H Tsujimoto; M Isahakia; M Hayami
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

7.  Reliable confirmation of antibodies to human immunodeficiency virus type 1 (HIV-1) with an enzyme-linked immunoassay using recombinant antigens derived from the HIV-1 gag, pol, and env genes.

Authors:  V L Ng; C S Chiang; C Debouck; M S McGrath; T H Grove; J Mills
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948

8.  Biological significance of the antibody response to HIV antigens expressed on the cell surface.

Authors:  J Goudsmit; K Ljunggren; L Smit; M Jondal; E M Fenyö; M Jonda
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

Review 9.  The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.

Authors:  Thomas S Postler; Ronald C Desrosiers
Journal:  J Virol       Date:  2012-10-17       Impact factor: 5.103

10.  Transmembrane envelope glycoproteins of human immunodeficiency virus type 2 and simian immunodeficiency virus SIV-mac exist as homodimers.

Authors:  M A Rey; A G Laurent; J McClure; B Krust; L Montagnier; A G Hovanessian
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103
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