| Literature DB >> 2414906 |
Abstract
An assay is described for detecting and measuring the capacity of a single virus particle to suppress completely the yield of interferon from a cell otherwise competent to product interferon. The assay defines virus populations in terms of a newly quantifiable attribute--interferon induction-suppressing particles (ISP). The antagonistic actions of interferon-inducing particles and interferon induction-suppressing particles are thought to determine the interferon-inducing capacity intrinsic to a virus population.Mesh:
Substances:
Year: 1985 PMID: 2414906 DOI: 10.1016/0042-6822(85)90349-6
Source DB: PubMed Journal: Virology ISSN: 0042-6822 Impact factor: 3.616