Literature DB >> 2414768

Native alpha 2-macroglobulin binds to a surface component of human placental trophoblast.

P M Johnson, P Arnaud, P Werner, R M Galbraith.   

Abstract

Immunofluorescence and radiobinding studies have shown that native human alpha 2-macroglobulin (alpha 2M), but not alpha 2M-trypsin complexes, binds to isolated human placental syncytiotrophoblast microvillous plasma membrane vesicles. Inhibition studies have indicated that alpha 2M may bind to a trophoblast surface protease. This interaction is of significance for the control of trophoblast invasiveness and haemostasis within the placental bed.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2414768     DOI： 10.1016/s0143-4004(85)80041-2

Source DB:  PubMed          Journal:  Placenta        ISSN： 0143-4004            Impact factor:   3.481


  1 in total

1.  Low-affinity receptors for tumour necrosis factor-alpha, interferon-gamma and granulocyte-macrophage colony-stimulating factor are expressed on human placental syncytiotrophoblast.

Authors:  J Hampson; P J McLaughlin; P M Johnson
Journal:  Immunology       Date:  1993-07       Impact factor: 7.397
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.