| Literature DB >> 24146522 |
Xin Ling Li1, Nong Xiao Fan, Hong Zhi Meng, Min Xue Shi, Ding Luo, Nan Ya Zhang.
Abstract
The objective of this study was to investigate the effectiveness and specific effects of acupuncture on ischemic-induced damage in rats after permanent middle cerebral artery occlusion. Cerebral ischemia was induced by middle cerebral artery occlusion in male Wistar rats. The rats were divided into the following 4 groups: normal controls, ischemic, real acupuncture-treated (Shuigou, DU26), and non-acupoint-treated groups. On the third postoperative day, neurological deficit scores, cerebral blood flow, infarction volume, and neuronal cell death counts were measured. In the real acupuncture-treated group, the neurological deficit scores and cerebral blood flow were improved (p < 0.05) and the infarction volume and neuronal cell death counts were reduced (p < 0.01) compared to the ischemic and non-acupoint-treated groups. The present study demonstrated that real acupuncture was effective against focal ischemia-induced damage in rats after middle cerebral artery occlusion, and the effects were specifically related to the right needling location.Entities:
Keywords: animal experimentation; middle cerebral artery occlusion; non-acupoint; real acupoint; specificity
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Year: 2013 PMID： 24146522 PMCID： PMC3794412 DOI： 10.4314/ajtcam.v10i4.30
Source DB: PubMed Journal: Afr J Tradit Complement Altern Med ISSN： 2505-0044