Literature DB >> 24146506

Analysis on 113 cases of adverse reactions caused by β-lactam antibiotics.

Jianquan Lu1, Chunyue Cai, Yufeng Gu, Yanhui Tang, Jinbiao Xue, Kaijian Huang.   

Abstract

UNLABELLED: The objectives of this study were to learn about the characteristics and rules of the occurrence of adverse reactions caused by lactam antibiotics and provide a reference for clinical drug use.
METHODS: A retrospective study was made to analyse the 113 case reports of adverse reactions caused by β-lactam antibiotics collected in our hospital between 2007 and 2009.
RESULTS: 113 cases of ADR involved 17 kinds of β-lactam antibiotics, headed by ceftriaxone sodium. The most common manifestation was skin and accessory damage; nervous system and gastrointestinal system damage were also easier to find, and the administration route was mainly intravenous infusion.
CONCLUSION: The clinical application of β-lactam antibiotics should pay attention to adverse reaction monitoring and rational drug use to reduce the incidence of adverse reactions.

Entities:  

Keywords:  adverse drug reactions; β-lactam antibiotics

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Year:  2013        PMID: 24146506      PMCID: PMC3794396          DOI: 10.4314/ajtcam.v10i4.14

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN: 2505-0044


  1 in total

Review 1.  Beta-lactam antibiotics: from antibiosis to resistance and bacteriology.

Authors:  Kok-Fai Kong; Lisa Schneper; Kalai Mathee
Journal:  APMIS       Date:  2010-01       Impact factor: 3.205

  1 in total

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