Literature DB >> 24146487

Study on in vitro anti-tumor activity of Bidens bipinnata L. extract.

Qing-Hui Yang1, Jun Yang, Guo-Ze Liu, Lei Wang, Tie-Chui Zhu, Hai-Li Gao, Xiao-Ge Kou.   

Abstract

We studied the in vitro anti-tumor activity of Bidens Bipinnata L. extract. MTT assay was used to investigate the inhibitory effect of different concentrations of the extracts on human hepatocellular carcinoma (HepG2) cell lines and human cervical carcinoma (Hela) cell lines, and the IC50 values were calculated. The Bidens Bipinnata L. extract had different degrees of inhibitory effects on these two cells, and when exposure time was 48 h, the inhibition rate reached its peak, with IC50 values of 14.80 µg/mL and 13.50 µg/mL respectively. The Bidens Bipinnata L. extract had a good inhibitory effect on human HepG2 cell lines and Hela cell lines, and thus has certain development prospects.

Entities:  

Keywords:  Bidens Bipinnata L.; MTT; anti-tumor; cell culture

Mesh:

Substances:

Year:  2013        PMID: 24146487      PMCID: PMC3777599     

Source DB:  PubMed          Journal:  Afr J Tradit Complement Altern Med        ISSN: 2505-0044


  2 in total

1.  Protection from oxidative damage using Bidens pilosa extracts in normal human erythrocytes.

Authors:  Hsin-Ling Yang; Ssu-Ching Chen; Nai-Wen Chang; Jia-Ming Chang; Mei-Ling Lee; Pei-Chuan Tsai; Han-Hsuan Fu; Wei-Wan Kao; Hsiao-Chi Chiang; Hsuan-Hui Wang; You-Cheng Hseu
Journal:  Food Chem Toxicol       Date:  2006-04-25       Impact factor: 6.023

2.  Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.

Authors:  Yi-Ming Chiang; Cicero Lee-Tian Chang; Shu-Lin Chang; Wen-Chin Yang; Lie-Fen Shyur
Journal:  J Ethnopharmacol       Date:  2006-10-19       Impact factor: 4.360

  2 in total
  2 in total

Review 1.  Development of Certain Protein Kinase Inhibitors with the Components from Traditional Chinese Medicine.

Authors:  Minghua Liu; Ge Zhao; Shousong Cao; Yangyang Zhang; Xiaofang Li; Xiukun Lin
Journal:  Front Pharmacol       Date:  2017-01-09       Impact factor: 5.810

2.  Total flavonoids of Bidens bipinnata L. ameliorate experimental adjuvant-induced arthritis through induction of synovial apoptosis.

Authors:  Ai-Zong Shen; Xia Li; Wei Hu; Fei-Hu Chen
Journal:  BMC Complement Altern Med       Date:  2015-12-15       Impact factor: 3.659

  2 in total

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