Literature DB >> 24145159

Heroin or conventional opioid maintenance? The patients' perspective.

Lena Karoline Bald1, Felix Bermpohl, Andreas Heinz, Jürgen Gallinat, Stefan Gutwinski.   

Abstract

OBJECTIVE: This study focused on the question whether patients with conventional opioid maintenance treatment (COMT) would prefer a switch to heroin maintenance treatment (HMT).
METHODS: We performed a region-wide anonymous survey of patients in the opioid maintenance program in Berlin, Germany. All 20 psychiatric hospitals and all 110 physicians' practices in Berlin licensed to offer COMT were approached to reach patients under COMT and also fulfilling the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) criteria of opiate dependence. The anonymous questionnaire focused on the question whether patients would prefer HMT to COMT. In our study, 986 of 5032 patients (19.6%) with COMT in Berlin participated. Of them, 881 (89.4%) patients gave information whether they would prefer HMT to COMT.
RESULTS: Of the participating patients, 40.9% would prefer HMT to COMT. These patients report more detoxification therapies (P < 0.001), a higher dose of methadone equivalent (P = 0.001), and more often continued use of multiple illegal drugs despite COMT (P < 0.001) than patients not preferring HMT. They also report less improvement in mental health (P < 0.001) and working abilities (P < 0.001) because of COMT than patients not preferring HMT.
CONCLUSIONS: The data on the patients' perspective complement the existing clinical studies, showing that previously unresponsive opioid-addicted patients especially would switch to HMT, whereas most patients would prefer continuation of COMT.

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Year:  2013        PMID: 24145159     DOI: 10.1097/ADM.0b013e3182a11ad0

Source DB:  PubMed          Journal:  J Addict Med        ISSN: 1932-0620            Impact factor:   3.702


  3 in total

1.  [Maintenance treatment in opioid-dependent patients with migration background].

Authors:  L K Bald; M Schouler-Ocak; S Penka; N Schoofs; T Häbel; F Bermpohl; S Gutwinski
Journal:  Nervenarzt       Date:  2016-05       Impact factor: 1.214

2.  Opioid tolerance in methadone maintenance treatment: comparison of methadone and levomethadone in long-term treatment.

Authors:  Stefan Gutwinski; Nikola Schoofs; Heiner Stuke; Thomas G Riemer; Corinde E Wiers; Felix Bermpohl
Journal:  Harm Reduct J       Date:  2016-02-16

Review 3.  New Approaches in Drug Dependence: Opioids.

Authors:  Juliane Mielau; Marc Vogel; Stefan Gutwinski; Inge Mick
Journal:  Curr Addict Rep       Date:  2021-05-26
  3 in total

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