| Literature DB >> 24144849 |
Yasodha Sivasothy1, Halijah Ibrahim, Audra Shaleena Paliany, Siti Aisyah Alias, Khalijah Awang.
Abstract
The rhizomes of Alpinia pahangensis Ridley yielded a new bis-labdanic diterpene for which the name pahangensin A (1) was proposed along with a new labdane diterpene, pahangensin B (2). Their structures were elucidated by spectroscopic methods including, 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Pahangensin A (1) was found to be an antibacterial agent against Staphylococcus aureus, Bacillus cereus and Bacillus subtilis with MIC values less than 100 μg/mL, respectively. Pahangensin B (2) exhibited antibacterial activity (MIC <100 μg/mL) against B. cereus.Entities:
Keywords: Alpinia pahangensis Ridley; Antibacterial agent; Bis-labdanic diterpene; Labdane diterpene; Pahangensin A; Pahangensin B; Zingiberaceae
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Year: 2013 PMID： 24144849 DOI： 10.1016/j.bmcl.2013.09.082
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823