Literature DB >> 24143372

Dexamethasone effects on activation and proliferation of immune memory T cells.

A A Gutsol1, N A Sokhonevich, V I Seledtsov, L S Litvinova.   

Abstract

Dose-dependent effects of dexamethasone on activation and proliferation of donor immune memory T cells (CD45RO(+)) were studied. Activation of memory T cells associated with IL-2 production and membrane expression of CD25 molecule was resistant to dexamethasone. Proliferative activity of memory T cells associated with membrane expression of CD71 molecule was highly sensitive to dexamethasone. Hence, glucocorticoid hormones can maintain the clonal balance in the lymphoid tissue without preventing realization of the immune memory mechanism.

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Year:  2013        PMID： 24143372     DOI： 10.1007/s10517-013-2182-5

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  4 in total

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2.  Glucocorticoids regulate natural killer cell function epigenetically.

Authors:  Justin L Eddy; Karen Krukowski; Linda Janusek; Herbert L Mathews
Journal:  Cell Immunol       Date:  2014-06-18       Impact factor: 4.868

3.  Glucocorticoids and Catecholamines Affect in Vitro Functionality of Porcine Blood Immune Cells.

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Journal:  Animals (Basel)       Date:  2019-08-12       Impact factor: 2.752

4.  Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages.

Authors:  Els Wauters; Pierre Van Mol; Abhishek Dinkarnath Garg; Sander Jansen; Johan Neyts; Joost Wauters; Yannick Van Herck; Lore Vanderbeke; Ayse Bassez; Bram Boeckx; Bert Malengier-Devlies; Anna Timmerman; Thomas Van Brussel; Tina Van Buyten; Rogier Schepers; Elisabeth Heylen; Dieter Dauwe; Christophe Dooms; Jan Gunst; Greet Hermans; Philippe Meersseman; Dries Testelmans; Jonas Yserbyt; Sabine Tejpar; Walter De Wever; Patrick Matthys; Junbin Qian; Diether Lambrechts
Journal:  Cell Res       Date:  2021-01-21       Impact factor: 46.297
  4 in total

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