Literature DB >> 24142045

A new Monte Carlo program for simulating light transport through Port Wine Stain skin.

T Lister1, P A Wright, P H Chappell.   

Abstract

A new Monte Carlo program is presented for simulating light transport through clinically normal skin and skin containing Port Wine Stain (PWS) vessels. The program consists of an eight-layer mathematical skin model constructed from optical coefficients described previously. A simulation including diffuse illumination at the surface and subsequent light transport through the model is carried out using a radiative transfer theory ray-tracing technique. Total reflectance values over 39 wavelengths are scored by the addition of simulated light returning to the surface within a specified region and surface reflections (calculated using Fresnel's equations). These reflectance values are compared to measurements from individual participants, and characteristics of the model are adjusted until adequate agreement is produced between simulated and measured skin reflectance curves. The absorption and scattering coefficients of the epidermis are adjusted through changes in the simulated concentrations and mean diameters of epidermal melanosomes to reproduce non-lesional skin colour. Pseudo-cylindrical horizontal vessels are added to the skin model, and their simulated mean depths, diameters and number densities are adjusted to reproduce measured PWS skin colour. Accurate reproductions of colour measurement data are produced by the program, resulting in realistic predictions of melanin and PWS blood vessel parameters. Using a modest personal computer, the simulation currently requires an average of five and a half days to complete.

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Year:  2013        PMID: 24142045     DOI: 10.1007/s10103-013-1443-x

Source DB:  PubMed          Journal:  Lasers Med Sci        ISSN: 0268-8921            Impact factor:   3.161


  29 in total

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Authors:  W Verkruysse; G W Lucassen; M J van Gemert
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Journal:  Physiol Meas       Date:  2002-11       Impact factor: 2.833

4.  The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour.

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Journal:  Br J Dermatol       Date:  2003-09       Impact factor: 9.302

5.  Modeling the effect of wavelength on the pulsed dye laser treatment of port wine stains.

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Journal:  Appl Opt       Date:  1993-02-01       Impact factor: 1.980

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Journal:  Opt Express       Date:  2009-02-02       Impact factor: 3.894

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Journal:  Appl Opt       Date:  2008-09-20       Impact factor: 1.980

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Journal:  Int J Cosmet Sci       Date:  2006-04       Impact factor: 2.970

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Authors:  M J van Gemert; S L Jacques; H J Sterenborg; W M Star
Journal:  IEEE Trans Biomed Eng       Date:  1989-12       Impact factor: 4.538

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Journal:  Photochem Photobiol       Date:  1984-08       Impact factor: 3.421

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  2 in total

1.  Experimental investigation on the vascular thermal response to near-infrared laser pulses.

Authors:  Dong Li; Bin Chen; Wenjuan Wu; Zhaoxia Ying
Journal:  Lasers Med Sci       Date:  2017-09-02       Impact factor: 3.161

2.  Photothermal treatment of port-wine stains using erythrocyte-derived particles doped with indocyanine green: a theoretical study.

Authors:  Joshua M Burns; Wangcun Jia; J Stuart Nelson; Boris Majaron; Bahman Anvari
Journal:  J Biomed Opt       Date:  2018-11       Impact factor: 3.170

  2 in total

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