Chiao-Hsiung Chuang1, Sheng-Hsiang Lin, Chiung-Yu Chen, Bor-Shyang Sheu, Ai-Wen Kao, Jung-Der Wang. 1. *Department of Internal Medicine, †Institute of Clinical Medicine, ‡Research Center of Clinical Medicine, §Department of Public Health, and ‖Department of Occupational and Environmental Medicine, Medical College and Hospital, National Cheng Kung University, Tainan, Taiwan.
Abstract
BACKGROUND: The incidence of inflammatory bowel disease is increasing worldwide, but data of epidemiological trends from low-endemic area are limited. As one of the low-endemic countries, we describe the trends of this disease in Taiwan over time. METHODS: This study was based on data obtained from the Catastrophic Illnesses Registration in the National Health Insurance Research Database, which covers more than 98% of the people in Taiwan. Every certificate of catastrophic illness must be approved by 2 expert gastroenterologists. Thirteen years (1998-2010) of data were analyzed for the trends of Crohn's disease (CD) and ulcerative colitis (UC). RESULTS: A total of 2915 incident cases (1818 men and 1097 women) were identified, including 2357 cases of UC and 558 cases of CD. The mean annual incidence rates were 0.80 for UC and 0.19 for CD per 100,000 inhabitants, with lifetime risks for those 20 to 79 years of age of 0.066% and 0.013%, respectively. The mean annual prevalence was 4.59 for UC and 1.05 for CD per 100,000 inhabitants. Poisson regression showed significantly increased trends during the observation period for both diseases, with a men/women ratio of 1.50 in UC and 2.14 in CD (P < 0.01). The mean age of individuals at diagnosis was higher for UC as compared with CD (44.7 versus 37.9, P < 0.001). CONCLUSIONS: Inflammatory bowel diseases are still relatively uncommon in Taiwan, but the incidence and prevalence rates are increasing.
BACKGROUND: The incidence of inflammatory bowel disease is increasing worldwide, but data of epidemiological trends from low-endemic area are limited. As one of the low-endemic countries, we describe the trends of this disease in Taiwan over time. METHODS: This study was based on data obtained from the Catastrophic Illnesses Registration in the National Health Insurance Research Database, which covers more than 98% of the people in Taiwan. Every certificate of catastrophic illness must be approved by 2 expert gastroenterologists. Thirteen years (1998-2010) of data were analyzed for the trends of Crohn's disease (CD) and ulcerative colitis (UC). RESULTS: A total of 2915 incident cases (1818 men and 1097 women) were identified, including 2357 cases of UC and 558 cases of CD. The mean annual incidence rates were 0.80 for UC and 0.19 for CD per 100,000 inhabitants, with lifetime risks for those 20 to 79 years of age of 0.066% and 0.013%, respectively. The mean annual prevalence was 4.59 for UC and 1.05 for CD per 100,000 inhabitants. Poisson regression showed significantly increased trends during the observation period for both diseases, with a men/women ratio of 1.50 in UC and 2.14 in CD (P < 0.01). The mean age of individuals at diagnosis was higher for UC as compared with CD (44.7 versus 37.9, P < 0.001). CONCLUSIONS:Inflammatory bowel diseases are still relatively uncommon in Taiwan, but the incidence and prevalence rates are increasing.
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Authors: Kirsten J Coppell; Ciarán P-C Galts; Fokko Y Huizing; Joanna K Norton; Andrew R Gray; Kim Schultz; Catherine E Hobbs; Kristina Aluzaite; Michael Schultz Journal: Inflamm Intest Dis Date: 2018-09-17
Authors: Hoonsub So; Byong Duk Ye; Young Soo Park; Jihun Kim; Joo Sung Kim; Won Moon; Kang-Moon Lee; You Sun Kim; Bora Keum; Seong-Eun Kim; Kyeong Ok Kim; Eun Soo Kim; Chang Kyun Lee; Sung Pil Hong; Jong Pil Im; Ja Seol Koo; Chang Hwan Choi; Jeong Eun Shin; Bo In Lee; Kyu Chan Huh; Young-Ho Kim; Hyun-Soo Kim; Young Sook Park; Dong Soo Han Journal: Intest Res Date: 2016-01-26