Literature DB >> 2414128

Primary structure of the beta-subunit of bovine transducin deduced from the cDNA sequence.

K Sugimoto, T Nukada, T Tanabe, H Takahashi, M Noda, N Minamino, K Kangawa, H Matsuo, T Hirose, S Inayama.   

Abstract

DNA complementary to the bovine retinal mRNA coding for the beta-subunit of transducin has been cloned by screening a cDNA library with oligodeoxyribonucleotide probes. Nucleotide sequence analysis of the cloned cDNA has revealed that this polypeptide consists of 340 amino acid residues (including the initiating methionine). Furthermore, cDNA hybridizable with a transducin beta-subunit cDNA probe has been cloned from a library derived from bovine brain poly(A)+ RNA. Comparison of the cloned cDNAs, in conjunction with blot hybridization analysis and S1 nuclease mapping of poly(A)+ RNA from bovine retina, brain and liver, suggests that the mRNAs coding for the beta-subunits of transducin and other guanine nucleotide binding proteins have the same protein-coding sequence but partly different 5'-noncoding sequences.

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Year:  1985        PMID： 2414128     DOI： 10.1016/0014-5793(85)80015-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  19 in total

1.  Retinal rods and cones have distinct G protein beta and gamma subunits.

Authors:  Y W Peng; J D Robishaw; M A Levine; K W Yau
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

2.  A Chlamydomonas gene encodes a G protein beta subunit-like polypeptide.

Authors:  J A Schloss
Journal:  Mol Gen Genet       Date:  1990-05

3.  Sequence of the beta-subunit of the phosphatidylinositol-specific phospholipase C-directed GTP-binding protein from squid (Loligo forbesi) photoreceptors.

Authors:  N J Ryba; J D Pottinger; J N Keen; J B Findlay
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

4.  Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide.

Authors:  M A Levine; P M Smallwood; P T Moen; L J Helman; T G Ahn
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

5.  Calmodulin binding distinguishes between beta gamma subunits of activated G proteins and transducin.

Authors:  L A Mangels; R R Neubig; H E Hamm; M E Gnegy
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

6.  Indirect immunofluorescence localization of beta-adrenergic receptors and G-proteins in human A431 cells.

Authors:  H Y Wang; M Berrios; C C Malbon
Journal:  Biochem J       Date:  1989-10-15       Impact factor: 3.857

7.  Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

Authors:  H Itoh; T Kozasa; S Nagata; S Nakamura; T Katada; M Ui; S Iwai; E Ohtsuka; H Kawasaki; K Suzuki
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

8.  Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning.

Authors:  H K Fong; T T Amatruda; B W Birren; M I Simon
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

9.  Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

Authors:  K P Van Meurs; C W Angus; S Lavu; H F Kung; S K Czarnecki; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

10.  MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae.

Authors:  R Ruggieri; K Tanaka; M Nakafuku; Y Kaziro; A Toh-e; K Matsumoto
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205
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