Literature DB >> 24140752

Monte Carlo investigation into feasibility and dosimetry of flat flattening filter free beams.

Sergei Zavgorodni1.   

Abstract

Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF (F4) beams without the use of a flattening filter (FF). Monte Carlo (MC) simulations with BEAMnrc and DOSXYZnrc codes have been performed to evaluate feasibility of this approach. The dose distributions in water for open 6 MV beams were simulated using the Varian 21EX linac head model, which will be called the FF model. The FF was then removed from the FF model, and MC simulations were performed using (1) 6 MeV electrons incident on the target and (2) a 6 MeV electron beam with electron angular distributions optimized to provide as flat dose profiles as possible. Configuration (1) represents FFF beam while configuration (2) allowed producing a F4 beam. Optimizations have also been performed to produce flattest profiles for a set of dose rates (DRs) in the range from 1.25 to 2.4 of the DR of FF beam. Profiles and percentage depth doses (PDDs) from 6 MV F4 beams have been calculated and compared to those from the FF beam. Calculated profiles demonstrated improved flatness of the FFF beams. In fact, up to field sizes within the circle of 35 cm diameter the flatness of F4 beam at dmax was better or comparable to that of FF beam. At 20 cm off-axis the dose increased from 52% for FFF to 92% for F4 beam. Also, profiles of F4 beams did not change considerably with depth. PDDs from F4 beams were similar to those of the FFF beam. The DR for the largest modeled (44 cm diameter) F4 beam was higher than the DR from FF beam by a factor of 1.25. It was shown that the DR can be increased while maintaining beam flatness, but at the cost of reduced field size.

Entities:  

Mesh:

Year:  2013        PMID: 24140752     DOI: 10.1088/0031-9155/58/21/7699

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  5 in total

1.  Reirradiation of nasopharyngeal carcinoma focusing on volumetric modulated arcs with flattening filter-free beams.

Authors:  M Zhuang; L Huang; D Zhu; X Peng; Z Lin
Journal:  Br J Radiol       Date:  2015-06-02       Impact factor: 3.039

2.  Evaluation of beam modeling for small fields using a flattening filter-free beam.

Authors:  Daisuke Kawahara; Shuichi Ozawa; Takeo Nakashima; Masamichi Aita; Shintaro Tsuda; Yusuke Ochi; Takuro Okumura; Hirokazu Masuda; Yoshimi Ohno; Yuji Murakami; Yasushi Nagata
Journal:  Radiol Phys Technol       Date:  2016-06-21

3.  The effect of beam shape on physical parameters of head and neck simultaneous-integrated boost intensity-modulated radiation therapy.

Authors:  Toshiro Tsubouchi; Masashi Yagi; Iori Sumida; Keisuke Tamari; Yuji Seo; Kazuhiko Ogawa
Journal:  Rep Pract Oncol Radiother       Date:  2018-09-04

4.  Comparative evaluation of modern dosimetry techniques near low- and high-density heterogeneities.

Authors:  Eyad A Alhakeem; Sami AlShaikh; Anatoly B Rosenfeld; Sergei F Zavgorodni
Journal:  J Appl Clin Med Phys       Date:  2015-09-08       Impact factor: 2.102

5.  Calculated relative biological effectiveness (RBE) for initial DNA double-strand breaks (DSB) from flattening filter and flattening filter-free 6 MV X-ray fields.

Authors:  Hisashi Nakano; Daisuke Kawahara; Satoshi Tanabe; Satoru Utsunomiya; Takeshi Takizawa; Madoka Sakai; Toshimichi Nakano; Atsushi Ohta; Motoki Kaidu; Hiroyuki Ishikawa
Journal:  BJR Open       Date:  2021-07-05
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.