| Literature DB >> 24139972 |
Abstract
High-throughput sequencing technologies are revolutionizing the life sciences. The past 12 months have seen a burst of genome sequences from non-model organisms, in each case representing a fundamental source of data of significant importance to biological research. This has bearing on several aspects of evolutionary biology, and we are now beginning to see patterns emerging from these studies. These include significant heterogeneity in the rate of recombination that affects adaptive evolution and base composition, the role of population size in adaptive evolution, and the importance of expansion of gene families in lineage-specific adaptation. Moreover, resequencing of population samples (population genomics) has enabled the identification of the genetic basis of critical phenotypes and cast light on the landscape of genomic divergence during speciation.Keywords: adaptive evolution; ecological genomics; evolutionary genomics; genome sequencing; molecular evolution; population genomics; positive selection; speciation genetics
Mesh:
Year: 2013 PMID: 24139972 DOI: 10.1016/j.tree.2013.09.008
Source DB: PubMed Journal: Trends Ecol Evol ISSN: 0169-5347 Impact factor: 17.712