Literature DB >> 24139972

Genome sequencing and population genomics in non-model organisms.

Hans Ellegren1.   

Abstract

High-throughput sequencing technologies are revolutionizing the life sciences. The past 12 months have seen a burst of genome sequences from non-model organisms, in each case representing a fundamental source of data of significant importance to biological research. This has bearing on several aspects of evolutionary biology, and we are now beginning to see patterns emerging from these studies. These include significant heterogeneity in the rate of recombination that affects adaptive evolution and base composition, the role of population size in adaptive evolution, and the importance of expansion of gene families in lineage-specific adaptation. Moreover, resequencing of population samples (population genomics) has enabled the identification of the genetic basis of critical phenotypes and cast light on the landscape of genomic divergence during speciation.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Keywords:  adaptive evolution; ecological genomics; evolutionary genomics; genome sequencing; molecular evolution; population genomics; positive selection; speciation genetics

Mesh:

Year:  2013        PMID: 24139972     DOI: 10.1016/j.tree.2013.09.008

Source DB:  PubMed          Journal:  Trends Ecol Evol        ISSN: 0169-5347            Impact factor:   17.712


  159 in total

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