Literature DB >> 24139395

Dynamins are forever: MxB inhibits HIV-1.

Otto Haller1.   

Abstract

Human MxA (MX1) protein is an interferon-induced restriction factor for a diverse range of viruses, whereas the related MxB (MX2) protein was thought to lack such activity. Three recent papers, including one in this issue of Cell Host & Microbe, show that MxB inhibits human immunodeficiency virus type 1 (HIV-1) infection.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24139395     DOI： 10.1016/j.chom.2013.10.002

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  15 in total

1.  Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal.

Authors:  Bianca Schulte; Cindy Buffone; Silvana Opp; Francesca Di Nunzio; Daniel Augusto De Souza Aranha Vieira; Alberto Brandariz-Nuñez; Felipe Diaz-Griffero
Journal:  J Virol       Date:  2015-06-10       Impact factor: 5.103

2.  Contribution of MxB oligomerization to HIV-1 capsid binding and restriction.

Authors:  Cindy Buffone; Bianca Schulte; Silvana Opp; Felipe Diaz-Griffero
Journal:  J Virol       Date:  2015-01-07       Impact factor: 5.103

3.  Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virus.

Authors:  Corinna Patzina; Otto Haller; Georg Kochs
Journal:  J Biol Chem       Date:  2014-01-21       Impact factor: 5.157

4.  MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.

Authors:  Silvana Opp; Daniel A S A Vieira; Bianca Schulte; Sumit K Chanda; Felipe Diaz-Griffero
Journal:  J Virol       Date:  2015-12-30       Impact factor: 5.103

Review 5.  PIP2: choreographer of actin-adaptor proteins in the HIV-1 dance.

Authors:  Vera Rocha-Perugini; Mónica Gordon-Alonso; Francisco Sánchez-Madrid
Journal:  Trends Microbiol       Date:  2014-04-23       Impact factor: 17.079

6.  Host and viral determinants of Mx2 antiretroviral activity.

Authors:  Idoia Busnadiego; Melissa Kane; Suzannah J Rihn; Hannah F Preugschas; Joseph Hughes; Daniel Blanco-Melo; Victoria P Strouvelle; Trinity M Zang; Brian J Willett; Chris Boutell; Paul D Bieniasz; Sam J Wilson
Journal:  J Virol       Date:  2014-04-23       Impact factor: 5.103

7.  Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.

Authors:  David C Goldstone; Philip A Walker; Lesley J Calder; Peter J Coombs; Joshua Kirkpatrick; Neil J Ball; Laura Hilditch; Melvyn W Yap; Peter B Rosenthal; Jonathan P Stoye; Ian A Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-16       Impact factor: 11.205

8.  MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1.

Authors:  Thomas Fricke; Tommy E White; Bianca Schulte; Daniel A de Souza Aranha Vieira; Adarsh Dharan; Edward M Campbell; Alberto Brandariz-Nuñez; Felipe Diaz-Griffero
Journal:  Retrovirology       Date:  2014-08-14       Impact factor: 4.602

9.  Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation.

Authors:  Michela Sabbatucci; Daniela Angela Covino; Cristina Purificato; Alessandra Mallano; Maurizio Federico; Jing Lu; Arturo Ottavio Rinaldi; Matteo Pellegrini; Roberta Bona; Zuleika Michelini; Andrea Cara; Stefano Vella; Sandra Gessani; Mauro Andreotti; Laura Fantuzzi
Journal:  Retrovirology       Date:  2015-01-22       Impact factor: 4.602

10.  Resistance to simian immunodeficiency virus low dose rectal challenge is associated with higher constitutive TRIM5α expression in PBMC.

Authors:  Hadega A Aamer; Premeela Rajakumar; Julia Nyaundi; Michael Murphey-Corb
Journal:  Retrovirology       Date:  2014-05-23       Impact factor: 4.602
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