Literature DB >> 2413916

Protons decrease the single channel conductance of the sarcoplasmic reticulum K+ channel in neutral and negatively charged bilayers.

J Bell.   

Abstract

The conductance of rabbit sarcoplasmic reticulum K+ channels incorporated into artificial bilayers of varying lipid composition was measured at different K+ and proton concentrations. Protons competitively inhibit the K+ conductance with a Ki of 0.5 microM. In negatively charged membranes, the conductance is well described by Gouy-Chapman-Stern theory modified to include the inhibitory effect of protons of the conductance and assuming that the channel mouth is isolated by 5-10 A from bilayer surface.

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Year:  1985        PMID： 2413916      PMCID： PMC1329328          DOI： 10.1016/S0006-3495(85)83790-5

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  10 in total

1.  Adsorption of monovalent cations to bilayer membranes containing negative phospholipids.

Authors:  M Eisenberg; T Gresalfi; T Riccio; S McLaughlin
Journal:  Biochemistry       Date:  1979-11-13       Impact factor: 3.162

2.  Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH.

Authors:  B Hille; A M Woodhull; B I Shapiro
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1975-06-10       Impact factor: 6.237

3.  Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties.

Authors:  M Montal; P Mueller
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

4.  Formation of ion channels by a negatively charged analog of gramicidin A.

Authors:  H J Apell; E Bamberg; H Alpes; P Läuger
Journal:  J Membr Biol       Date:  1977-02-24       Impact factor: 1.843

5.  Single channel potassium currents of the anomalous rectifier.

Authors:  Y Fukushima
Journal:  Nature       Date:  1981-11-26       Impact factor: 49.962

6.  Effects of phospholipid surface charge on ion conduction in the K+ channel of sarcoplasmic reticulum.

Authors:  J E Bell; C Miller
Journal:  Biophys J       Date:  1984-01       Impact factor: 4.033

7.  The effect of surface charge on the voltage-dependent conductance induced in thin lipid membranes by monazomycin.

Authors:  R U Muller; A Finkelstein
Journal:  J Gen Physiol       Date:  1972-09       Impact factor: 4.086

8.  Channel-mediated monovalent cation fluxes in isolated sarcoplasmic reticulum vesicles.

Authors:  A M Garcia; C Miller
Journal:  J Gen Physiol       Date:  1984-06       Impact factor: 4.086

9.  Magnitude and location of surface charges on Myxicola giant axons.

Authors:  T Begenisich
Journal:  J Gen Physiol       Date:  1975-07       Impact factor: 4.086

10.  Acetylcholine receptor in planar lipid bilayers. Characterization of the channel properties of the purified nicotinic acetylcholine receptor from Torpedo californica reconstituted in planar lipid bilayers.

Authors:  P Labarca; J Lindstrom; M Montal
Journal:  J Gen Physiol       Date:  1984-04       Impact factor: 4.086
  10 in total
  4 in total

1.  Passive and active membrane properties of mudpuppy taste receptor cells.

Authors:  S C Kinnamon; S D Roper
Journal:  J Physiol       Date:  1987-02       Impact factor: 5.182

2.  Cations mediate interactions between the nicotinic acetylcholine receptor and anionic lipids.

Authors:  Raymond M Sturgeon; John E Baenziger
Journal:  Biophys J       Date:  2010-03-17       Impact factor: 4.033

Review 3.  New and notable ion-channels in the sarcoplasmic/endoplasmic reticulum: do they support the process of intracellular Ca²⁺ release?

Authors:  Hiroshi Takeshima; Elisa Venturi; Rebecca Sitsapesan
Journal:  J Physiol       Date:  2014-11-17       Impact factor: 5.182

4.  Enhanced activity of multiple TRIC-B channels: an endoplasmic reticulum/sarcoplasmic reticulum mechanism to boost counterion currents.

Authors:  Fiona O'Brien; David Eberhardt; Katja Witschas; Sam El-Ajouz; Tsunaki Iida; Miyuki Nishi; Hiroshi Takeshima; Rebecca Sitsapesan; Elisa Venturi
Journal:  J Physiol       Date:  2019-04-14       Impact factor: 5.182
  4 in total

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