Literature DB >> 2413881

Effects of terminal mismatches on RNA stability: thermodynamics of duplex formation for ACCGGGp, ACCGGAp, and ACCGGCp.

D R Hickey, D H Turner.   

Abstract

The thermodynamics of ACCGGCp, ACCGGAp, and ACCGGGp helix formation have been measured in 1 M NaCl. The terminal mispairs stabilize the CCGG core duplex at 10(-4) M in the order AC approximately equal to AA less than AG approximately equal to AU. The data reported provide thermodynamic parameters for RNA structure prediction and suggest useful approximations for including other mismatches in current algorithms.

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Year:  1985        PMID: 2413881     DOI: 10.1021/bi00336a028

Source DB:  PubMed          Journal:  Biochemistry        ISSN: 0006-2960            Impact factor:   3.162


  4 in total

1.  Stability of single-nucleotide bulge loops embedded in a GAAA RNA hairpin stem.

Authors:  Geoffrey F S Lim; Gregory E Merz; Michael D McCann; Jocelyn M Gruskiewicz; Martin J Serra
Journal:  RNA       Date:  2012-02-16       Impact factor: 4.942

2.  Characterization of RNA hairpin loop stability.

Authors:  D R Groebe; O C Uhlenbeck
Journal:  Nucleic Acids Res       Date:  1988-12-23       Impact factor: 16.971

3.  Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

Authors:  M Kozak
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

4.  Helix capping in RNA structure.

Authors:  Jung C Lee; Robin R Gutell
Journal:  PLoS One       Date:  2014-04-01       Impact factor: 3.240

  4 in total

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