| Literature DB >> 2413881 |
Abstract
The thermodynamics of ACCGGCp, ACCGGAp, and ACCGGGp helix formation have been measured in 1 M NaCl. The terminal mispairs stabilize the CCGG core duplex at 10(-4) M in the order AC approximately equal to AA less than AG approximately equal to AU. The data reported provide thermodynamic parameters for RNA structure prediction and suggest useful approximations for including other mismatches in current algorithms.Entities:
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Year: 1985 PMID: 2413881 DOI: 10.1021/bi00336a028
Source DB: PubMed Journal: Biochemistry ISSN: 0006-2960 Impact factor: 3.162