Literature DB >> 2413841

The action of actinomycin D on the transcription of T7 coliphage DNA by Escherichia coli RNA polymerase.

P A Flamée.   

Abstract

An actinomycin D molecule bound to DNA sometimes stops the synthesis of RNA by Escherichia coli RNA polymerase. However, quite often, the bound antibiotic is released before the RNA polymerase detaches from the template DNA, so that the enzyme can resume, without interruption, the synthesis of the RNA chain.

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Year:  1985        PMID： 2413841      PMCID： PMC1152650          DOI： 10.1042/bj2300557

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  A quantitative assay for bacterial RNA polymerases.

Authors:  M J Chamberlin; W C Nierman; J Wiggs; N Neff
Journal:  J Biol Chem       Date:  1979-10-25       Impact factor: 5.157

2.  An expanded transcriptional map of T7 bacteriophage. Reading of minor T7 promoter sites in vitro by Escherichia coli RNA polymerase.

Authors:  S J Stahl; M J Chamberlin
Journal:  J Mol Biol       Date:  1977-06-05       Impact factor: 5.469

3.  Immediate inactivation of T7 coliphage treated by monofunctional alkylating agents.

Authors:  W G Verly; P Crine; P Bannon; A Forget
Journal:  Biochim Biophys Acta       Date:  1974-05-17

4.  Studies of the binding of actinomycin and related compounds to DNA.

Authors:  W Müller; D M Crothers
Journal:  J Mol Biol       Date:  1968-07-28       Impact factor: 5.469

5.  Optical properties of actinomycin D. I. Influence of the lactone rings on its optical activity.

Authors:  H Ziffer; K Yamaoka; A B Mauger
Journal:  Biochemistry       Date:  1968-03       Impact factor: 3.162

6.  Kinetics of the in vitro inhibition of transcription by actinomycin.

Authors:  R W Hyman; N Davidson
Journal:  J Mol Biol       Date:  1970-06-14       Impact factor: 5.469

7.  Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elements.

Authors:  J J Dunn; F W Studier
Journal:  J Mol Biol       Date:  1983-06-05       Impact factor: 5.469

8.  Action of intact AP (apurinic/apyrimidinic) sites and AP sites associated with breaks on the transcription of T7 coliphage DNA by Escherichia coli RNA polymerase.

Authors:  P A Flamée; W G Verly
Journal:  Biochem J       Date:  1985-07-01       Impact factor: 3.857
  8 in total
  1 in total

1.  Metastasis-associated protein 1 drives tumor cell migration and invasion through transcriptional repression of RING finger protein 144A.

Authors:  Hezlin Marzook; Da-Qiang Li; Vasudha S Nair; Prakriti Mudvari; Sirigiri Divijendra Natha Reddy; Suresh B Pakala; T R Santhoshkumar; M Radhakrishna Pillai; Rakesh Kumar
Journal:  J Biol Chem       Date:  2011-12-19       Impact factor: 5.157
  1 in total

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