Literature DB >> 2413742

Effect of rat and beta-human interferons on hyperacute experimental allergic encephalomyelitis in rats.

F Hertz, R Deghenghi.   

Abstract

Human interferon-beta (human IFN-beta) and rat interferon (rat IFN) were evaluated on experimental allergic encephalomyelitis (EAE) in rats, a delayed cellular reaction resembling human multiple sclerosis (MS). Rat IFN was active by intravenous and intracerebroventricular routes. It decreased the severity of clinical symptoms of paralysis during the 22 days of the assay. Human IFN-beta, on the contrary, had no effect when similarly tested in this rat model. Cyclophosphamide delayed the onset of paralysis, but levamisole enhanced the severity of the EAE.

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Year:  1985        PMID： 2413742     DOI： 10.1007/bf01982879

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  33 in total

1.  Production of high-titered interferon in cultures of human diploid cells.

Authors:  E A Havell; J Vilcek
Journal:  Antimicrob Agents Chemother       Date:  1972-12       Impact factor: 5.191

2.  Passive transfer of adjuvant-induced arthritis and allergic encephalomyelitis in rats using thoracic duct lymphocytes.

Authors:  D J Whitehouse; M W Whitehouse; C M Pearson
Journal:  Nature       Date:  1969-12-27       Impact factor: 49.962

3.  Inhibition of passive localized experimental allergic encephalomyelitis by interferon.

Authors:  S L Abreu; J Tondreau; S Levine; R Sowinski
Journal:  Int Arch Allergy Appl Immunol       Date:  1983

4.  Immuno-modulating properties of interferons.

Authors:  E De Maeyer; J De Maeyer-Guignard
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1982-09-24       Impact factor: 6.237

5.  Interferon in cancer: Faith, hope and reality.

Authors:  H Strander; S Einhorn
Journal:  Am J Clin Oncol       Date:  1982-06       Impact factor: 2.339

6.  Pharmacokinetics of rat fibroblast interferon.

Authors:  S L Abreu
Journal:  J Pharmacol Exp Ther       Date:  1983-07       Impact factor: 4.030

7.  Purification of highly radioactive mouse interferon produced by Ehrlich ascites tumour cells induced by Sendai virus.

Authors:  E Dussaix; A Gregoire; C Chany; D C Thang; M N Thang
Journal:  J Gen Virol       Date:  1983-02       Impact factor: 3.891

8.  Chemical prevention of experimental allergic encephalomyelitis in rats: a quantitative evaluation of steroids and various non-steroid drugs.

Authors:  A Komarek; F M Dietrich
Journal:  Arch Int Pharmacodyn Ther       Date:  1971-10

9.  The encephalomyelitic activity of myelin isolated by ultracentrifugation.

Authors:  R H LAATSCH; M W KIES; S GORDON; E C ALVORD
Journal:  J Exp Med       Date:  1962-04-01       Impact factor: 14.307
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  7 in total

Review 1.  Mechanisms of action of interferon-beta in multiple sclerosis.

Authors:  B G Arnason; A Dayal; Z X Qu; M A Jensen; K Genç; A T Reder
Journal:  Springer Semin Immunopathol       Date:  1996

2.  IFN-β Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis.

Authors:  Duncheng Wang; Debjani Ghosh; S M Touhidul Islam; Cody D Moorman; Ashton E Thomason; Daniel S Wilkinson; Mark D Mannie
Journal:  J Immunol       Date:  2016-09-12       Impact factor: 5.422

Review 3.  Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).

Authors:  Cris S Constantinescu; Nasr Farooqi; Kate O'Brien; Bruno Gran
Journal:  Br J Pharmacol       Date:  2011-10       Impact factor: 8.739

Review 4.  Interferons in relapsing-remitting multiple sclerosis: are there benefits from long-term use?

Authors:  Oscar Fernández
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

Review 5.  Preclinical safety testing of species-specific proteins produced with recombinant DNA-techniques. An attempt to transfer current experience into future testing strategies.

Authors:  K Teelmann; C Hohbach; H Lehmann
Journal:  Arch Toxicol       Date:  1986-12       Impact factor: 5.153

Review 6.  Anti-inflammatory properties of Type I interferons.

Authors:  Alfons Billiau
Journal:  Antiviral Res       Date:  2006-04-04       Impact factor: 5.970

7.  Multicentre double-blind study of effect of intrathecally administered natural human fibroblast interferon on exacerbations of multiple sclerosis.

Authors:  L Jacobs; A M Salazar; R Herndon; P A Reese; A Freeman; R Josefowicz; A Cuetter; F Husain; W A Smith; R Ekes
Journal:  Lancet       Date:  1986 Dec 20-27       Impact factor: 79.321
  7 in total

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