Literature DB >> 24135620

Reintervention after thoracic endovascular aortic repair of complicated aortic dissection.

Elsa M Faure1, Ludovic Canaud2, Camille Agostini3, Roxane Shaub3, Gudrun Böge4, Charles Marty-ané4, Pierre Alric2.   

Abstract

OBJECTIVE: This study assessed predictive factors for reintervention after thoracic endovascular aortic repair (TEVAR) for complicated aortic dissection (C-AD).
METHODS: An institutional review of consecutive TEVAR for C-AD was performed.
RESULTS: Between 2000 and 2011, 41 patients underwent TEVAR for a C-AD involving the descending thoracic aorta. Primary indications included aneurysm >55 mm in 24, rapid aneurysmal enlargement or impending rupture in 6, saccular aneurysm >20 mm in 1, malperfusion in 1, intractable chest pain in 3, and rupture in 6. Technical success was achieved in 100%. The 30-day mortality rate was 5% (n = 2). Fourteen secondary procedures were performed in 13 patients (32%) for indications of device migration in 2, proximal type I endoleak in 5, distal type I endoleak in 2, type II endoleak in 1, aneurysmal evolution of the descending thoracic aorta in 2, aneurysmal expansion of the dissected abdominal aorta in 1, and retrograde dissection in 1. Multivariate analysis demonstrated that oversizing ≥20% (odds ratio [OR], 16; P = .011), bare-spring stent in the proximal landing zone of the stent graft (OR, 12; P = .032), and anticoagulant therapy (OR, 78; P = .03) were significant factors for reintervention. On univariate analysis, large aneurysm was a risk factor for reintervention (P = .002), whereas complete false lumen thrombosis at the stent graft level was protective (P < .05).
CONCLUSIONS: This study confirms the feasibility of TEVAR for C-AD, although the rate of reintervention is high. Excessive oversizing, a bare-spring stent graft in the proximal landing zone, large aortic dilatation, and anticoagulant therapy were factors associated with reintervention. Complete false lumen thrombosis at the stent graft level was protective.
Copyright © 2014 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2013        PMID: 24135620     DOI: 10.1016/j.jvs.2013.08.089

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


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5.  Endovascular repair of acute complicated type B aortic dissection-systematic review and meta-analysis of long-term survival and reintervention.

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10.  Comparison of gene expression profiles in aortic dissection and normal human aortic tissues.

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