Literature DB >> 24135276

EGFR and EGFRvIII in glioblastoma: partners in crime.

Gelareh Zadeh1, Krishna P L Bhat, Kenneth Aldape.   

Abstract

EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis, but the underlying mechanisms have remained elusive. In this issue of Cancer Cell, Weiss and colleagues implicate phosphorylation of EGFRvIII by EGFR and the consequent phosphorylation of STAT3 as a signaling axis that drives transformation in glioblastoma.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24135276     DOI： 10.1016/j.ccr.2013.09.017

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  25 in total

1.  Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.

Authors:  Stefan Klingler; Baofeng Guo; Jun Yao; Haiyan Yan; Ling Zhang; Angelina V Vaseva; Sida Chen; Peter Canoll; James W Horner; Y Alan Wang; Ji-Hye Paik; Haoqiang Ying; Hongwu Zheng
Journal:  Cancer Res       Date:  2015-03-25       Impact factor: 12.701

Review 2.  CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

Authors:  Brooke L Prinzing; Stephen M Gottschalk; Giedre Krenciute
Journal:  Expert Rev Anticancer Ther       Date:  2018-03-16       Impact factor: 4.512

Review 3.  Non-canonical signaling mode of the epidermal growth factor receptor family.

Authors:  Heng-Huan Lee; Ying-Nai Wang; Mien-Chie Hung
Journal:  Am J Cancer Res       Date:  2015-09-15       Impact factor: 6.166

4.  MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells.

Authors:  Sarmistha Talukdar; Anjan K Pradhan; Praveen Bhoopathi; Xue-Ning Shen; Laura A August; Jolene J Windle; Devanand Sarkar; Frank B Furnari; Webster K Cavenee; Swadesh K Das; Luni Emdad; Paul B Fisher
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-14       Impact factor: 11.205

5.  Control of glioblastoma tumorigenesis by feed-forward cytokine signaling.

Authors:  Arezu Jahani-Asl; Hang Yin; Vahab D Soleimani; Takrima Haque; H Artee Luchman; Natasha C Chang; Marie-Claude Sincennes; Sidharth V Puram; Andrew M Scott; Ian A J Lorimer; Theodore J Perkins; Keith L Ligon; Samuel Weiss; Michael A Rudnicki; Azad Bonni
Journal:  Nat Neurosci       Date:  2016-04-25       Impact factor: 24.884

6.  Extracellular Hyaluronic Acid Influences the Efficacy of EGFR Tyrosine Kinase Inhibitors in a Biomaterial Model of Glioblastoma.

Authors:  Sara Pedron; Jacob S Hanselman; Mark A Schroeder; Jann N Sarkaria; Brendan A C Harley
Journal:  Adv Healthc Mater       Date:  2017-08-02       Impact factor: 9.933

7.  Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients.

Authors:  Javier M Figueroa; Johan Skog; Johnny Akers; Hongying Li; Ricardo Komotar; Randy Jensen; Florian Ringel; Isaac Yang; Steven Kalkanis; Reid Thompson; Lori LoGuidice; Emily Berghoff; Andrew Parsa; Linda Liau; William Curry; Daniel Cahill; Chetan Bettegowda; Frederick F Lang; E Antonio Chiocca; John Henson; Ryan Kim; Xandra Breakefield; Clark Chen; Karen Messer; Fred Hochberg; Bob S Carter
Journal:  Neuro Oncol       Date:  2017-10-19       Impact factor: 12.300

8.  MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme.

Authors:  Alexandra Sufit; Alisa B Lee-Sherick; Deborah DeRyckere; Manali Rupji; Bhakti Dwivedi; Marileila Varella-Garcia; Angela M Pierce; Jeanne Kowalski; Xiaodong Wang; Stephen V Frye; H Shelton Earp; Amy K Keating; Douglas K Graham
Journal:  PLoS One       Date:  2016-10-26       Impact factor: 3.240

Review 9.  Single-cell analysis tools for drug discovery and development.

Authors:  James R Heath; Antoni Ribas; Paul S Mischel
Journal:  Nat Rev Drug Discov       Date:  2015-12-16       Impact factor: 112.288

10.  Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro.

Authors:  Mikkel Staberg; Signe Regner Michaelsen; Louise Stobbe Olsen; Mette Kjølhede Nedergaard; Mette Villingshøj; Marie-Thérése Stockhausen; Petra Hamerlik; Hans Skovgaard Poulsen
Journal:  Cancer Cell Int       Date:  2016-04-26       Impact factor: 5.722
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