Literature DB >> 24135275

NF-κB: a coordinator for epigenetic regulation by MLL.

Susumu Goyama1, James C Mulloy.   

Abstract

NF-κB is involved in a variety of biological processes, including cancer development. In this issue of Cancer Cell, Kuo et al. show the essential role for IKK/NF-κB signaling in epigenetic regulation by MLL oncoproteins to maintain leukemia stem cells.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24135275      PMCID： PMC4147035          DOI： 10.1016/j.ccr.2013.09.016

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

1.  Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF.

Authors:  Nahoko Nishimoto; Shunya Arai; Motoshi Ichikawa; Masahiro Nakagawa; Susumu Goyama; Keiki Kumano; Tsuyoshi Takahashi; Yasuhiko Kamikubo; Yoichi Imai; Mineo Kurokawa
Journal:  Blood       Date:  2011-07-14       Impact factor: 22.113

Review 2.  Shared principles in NF-kappaB signaling.

Authors:  Matthew S Hayden; Sankar Ghosh
Journal:  Cell       Date:  2008-02-08       Impact factor: 41.582

3.  The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.

Authors:  Gang Huang; Xinghui Zhao; Lan Wang; Shannon Elf; Hao Xu; Xinyang Zhao; Goro Sashida; Yue Zhang; Yan Liu; Jennifer Lee; Silvia Menendez; Youyang Yang; Xiaomei Yan; Pu Zhang; Daniel G Tenen; Motomi Osato; James J-D Hsieh; Stephen D Nimer
Journal:  Blood       Date:  2011-10-19       Impact factor: 22.113

4.  Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Authors:  Benjamin Mizukawa; Junping Wei; Mahesh Shrestha; Mark Wunderlich; Fu-Sheng Chou; Andrea Griesinger; Chad E Harris; Ashish R Kumar; Yi Zheng; David A Williams; James C Mulloy
Journal:  Blood       Date:  2011-09-22       Impact factor: 22.113

5.  Epigenetic roles of MLL oncoproteins are dependent on NF-κB.

Authors:  Hsu-Ping Kuo; Zhong Wang; Dung-Fang Lee; Masayuki Iwasaki; Jesus Duque-Afonso; Stephen H K Wong; Chiou-Hong Lin; Maria E Figueroa; Jie Su; Ihor R Lemischka; Michael L Cleary
Journal:  Cancer Cell       Date:  2013-09-19       Impact factor: 31.743

6.  Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells.

Authors:  Shunya Arai; Akihide Yoshimi; Munetake Shimabe; Motoshi Ichikawa; Masahiro Nakagawa; Yoichi Imai; Susumu Goyama; Mineo Kurokawa
Journal:  Blood       Date:  2010-12-29       Impact factor: 22.113

7.  The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

Authors:  Yingzi Wang; Andrei V Krivtsov; Amit U Sinha; Trista E North; Wolfram Goessling; Zhaohui Feng; Leonard I Zon; Scott A Armstrong
Journal:  Science       Date:  2010-03-26       Impact factor: 47.728

8.  AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors.

Authors:  Masahiro Nakagawa; Munetake Shimabe; Naoko Watanabe-Okochi; Shunya Arai; Akihide Yoshimi; Akihito Shinohara; Nahoko Nishimoto; Keisuke Kataoka; Tomohiko Sato; Keiki Kumano; Yasuhito Nannya; Motoshi Ichikawa; Yoichi Imai; Mineo Kurokawa
Journal:  Blood       Date:  2011-10-21       Impact factor: 22.113

9.  Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Authors:  Junping Wei; Mark Wunderlich; Catherine Fox; Sara Alvarez; Juan C Cigudosa; Jamie S Wilhelm; Yi Zheng; Jose A Cancelas; Yi Gu; Michael Jansen; Jorge F Dimartino; James C Mulloy
Journal:  Cancer Cell       Date:  2008-06       Impact factor: 31.743

Review 10.  Recent progress toward epigenetic therapies: the example of mixed lineage leukemia.

Authors:  Tobias Neff; Scott A Armstrong
Journal:  Blood       Date:  2013-05-06       Impact factor: 22.113
  10 in total
  3 in total

1.  Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.

Authors:  Mark Sausen; Jillian Phallen; Vilmos Adleff; Siân Jones; Rebecca J Leary; Michael T Barrett; Valsamo Anagnostou; Sonya Parpart-Li; Derek Murphy; Qing Kay Li; Carolyn A Hruban; Rob Scharpf; James R White; Peter J O'Dwyer; Peter J Allen; James R Eshleman; Craig B Thompson; David S Klimstra; David C Linehan; Anirban Maitra; Ralph H Hruban; Luis A Diaz; Daniel D Von Hoff; Julia S Johansen; Jeffrey A Drebin; Victor E Velculescu
Journal:  Nat Commun       Date:  2015-07-07       Impact factor: 14.919

2.  Mitogen-activated protein kinase binding protein 1 (MAPKBP1) is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia.

Authors:  Lin Fu; Jinlong Shi; Kai Hu; Jijun Wang; Weidong Wang; Xiaoyan Ke
Journal:  Oncotarget       Date:  2015-04-10

3.  Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF-κB target gene expression in human microglia.

Authors:  Min Yin; Zhiying Chen; Yetong Ouyang; Huiyan Zhang; Zhigang Wan; Han Wang; Wei Wu; Xiaoping Yin
Journal:  J Neuroinflammation       Date:  2017-06-29       Impact factor: 8.322
  3 in total

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