Literature DB >> 24134815

[The rheumatoid hand].

Julien Henry1, Eric Roulot, Cécile Gaujoux-Viala.   

Abstract

Rheumatoid arthritis usually affects the hand (90%). Without treatment, joint damages and deformities lead to loss of the ability to grip, grasp, and pinch, often leaving the patient unable to perform the activities of daily living. Early treatment with DMARDs ± physical therapy is the best way to control the disease and prevent deformity, as well as disability, which often occurs when joints get damaged. Two decades later dramatic advances have been made in the medical therapy of RA with the expanded range of effective disease-modifying antirheumatic drugs. When a patient with RA develops joint damages in the hand or wrist that are unresponsive to medical management and injections therapy, surgical intervention may be necessary. Optimal care involves a team approach among the patient involving rheumatologists, physical therapists and hand surgeons. Patients with RA should be closely monitored in order to detect joint damages necessitating physical therapist or hand surgeon consultation.
Copyright © 2013. Published by Elsevier Masson SAS.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24134815     DOI: 10.1016/j.lpm.2012.08.007

Source DB:  PubMed          Journal:  Presse Med        ISSN: 0755-4982            Impact factor:   1.228


  1 in total

1.  uPAR promotes tumor-like biologic behaviors of fibroblast-like synoviocytes through PI3K/Akt signaling pathway in patients with rheumatoid arthritis.

Authors:  Yan Liu; Yun Feng Pan; You-Qiu Xue; Lin-Kai Fang; Xing-Hua Guo; Xin Guo; Meng Liu; Bi-Yao Mo; Meng-Ru Yang; Fang Liu; Yun-Ting Wu; Nancy Olsen; Song Guo Zheng
Journal:  Cell Mol Immunol       Date:  2017-01-16       Impact factor: 11.530

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.