Literature DB >> 24132331

Drug discovery: Structure-led design.

Monica Hoyos Flight.   

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Year:  2013        PMID： 24132331     DOI： 10.1038/502S50a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  7 in total

Review 1.  Therapeutic antibodies directed at G protein-coupled receptors.

Authors:  Catherine J Hutchings; Markus Koglin; Fiona H Marshall
Journal:  MAbs       Date:  2010-11-01       Impact factor: 5.857

2.  Structure of class B GPCR corticotropin-releasing factor receptor 1.

Authors:  Kaspar Hollenstein; James Kean; Andrea Bortolato; Robert K Y Cheng; Andrew S Doré; Ali Jazayeri; Robert M Cooke; Malcolm Weir; Fiona H Marshall
Journal:  Nature       Date:  2013-07-17       Impact factor: 49.962

Review 3.  Development of M1 mAChR allosteric and bitopic ligands: prospective therapeutics for the treatment of cognitive deficits.

Authors:  Briana J Davie; Arthur Christopoulos; Peter J Scammells
Journal:  ACS Chem Neurosci       Date:  2013-05-23       Impact factor: 4.418

4.  Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists.

Authors:  Xin Chen; Maria F Sassano; Lianyou Zheng; Vincent Setola; Meng Chen; Xu Bai; Stephen V Frye; William C Wetsel; Bryan L Roth; Jian Jin
Journal:  J Med Chem       Date:  2012-08-13       Impact factor: 7.446

5.  Structure of the human glucagon class B G-protein-coupled receptor.

Authors:  Fai Yiu Siu; Min He; Chris de Graaf; Gye Won Han; Dehua Yang; Zhiyun Zhang; Caihong Zhou; Qingping Xu; Daniel Wacker; Jeremiah S Joseph; Wei Liu; Jesper Lau; Vadim Cherezov; Vsevolod Katritch; Ming-Wei Wang; Raymond C Stevens
Journal:  Nature       Date:  2013-07-17       Impact factor: 49.962

6.  Structure of the human smoothened receptor bound to an antitumour agent.

Authors:  Chong Wang; Huixian Wu; Vsevolod Katritch; Gye Won Han; Xi-Ping Huang; Wei Liu; Fai Yiu Siu; Bryan L Roth; Vadim Cherezov; Raymond C Stevens
Journal:  Nature       Date:  2013-05-01       Impact factor: 49.962

7.  Crystal structure of the β2 adrenergic receptor-Gs protein complex.

Authors:  Søren G F Rasmussen; Brian T DeVree; Yaozhong Zou; Andrew C Kruse; Ka Young Chung; Tong Sun Kobilka; Foon Sun Thian; Pil Seok Chae; Els Pardon; Diane Calinski; Jesper M Mathiesen; Syed T A Shah; Joseph A Lyons; Martin Caffrey; Samuel H Gellman; Jan Steyaert; Georgios Skiniotis; William I Weis; Roger K Sunahara; Brian K Kobilka
Journal:  Nature       Date:  2011-07-19       Impact factor: 49.962
  7 in total
  2 in total

1.  Identification and evaluation of network modules for the prognosis of basal-like breast cancer.

Authors:  Robin M Hallett; Jessica G Cockburn; Brian Li; Anna Dvorkin-Gheva; John A Hassell; Anita Bane
Journal:  Oncotarget       Date:  2015-07-10

2.  Virtual Screening and Molecular Dynamics Study of Potential Negative Allosteric Modulators of mGluR1 from Chinese Herbs.

Authors:  Ludi Jiang; Xianbao Zhang; Xi Chen; Yusu He; Liansheng Qiao; Yanling Zhang; Gongyu Li; Yuhong Xiang
Journal:  Molecules       Date:  2015-07-15       Impact factor: 4.411
  2 in total

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