Literature DB >> 2413205

Recombinant human gamma-interferon in primary hepatocellular carcinoma.

A Forbes, P J Johnson, R Williams.   

Abstract

A phase II trial of recombinant human gamma-interferon in the treatment of unresectable primary hepatocellular carcinoma is reported. The trial was terminated prematurely after recruitment of only 7 patients because of unacceptable toxicity, predominantly renal. There was no evidence of response in any of the 7 patients but some evidence that disease progression was more rapid during the treatment period.

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Year:  1985        PMID: 2413205      PMCID: PMC1289947          DOI: 10.1177/014107688507801007

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   5.344


  9 in total

1.  Interferon: antitumor actions.

Authors:  W R Fleischmann; G R Klimpel; S K Tyring; S Baron
Journal:  Transplant Proc       Date:  1984-04       Impact factor: 1.066

2.  Current status of interferon therapy.

Authors:  P A Gatenby; A Basten
Journal:  Med J Aust       Date:  1984-04-14       Impact factor: 7.738

3.  Toxic effects of interferon.

Authors:  R R Oldham
Journal:  Science       Date:  1983-02-25       Impact factor: 47.728

4.  Interferon and cancer.

Authors:  K Sikora; H Smedley
Journal:  Br Med J (Clin Res Ed)       Date:  1983-03-05

5.  The kidney and liver diseases.

Authors:  S P Wilkinson
Journal:  J Clin Pathol       Date:  1981-11       Impact factor: 3.411

6.  Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation.

Authors:  E Rinderknecht; B H O'Connor; H Rodriguez
Journal:  J Biol Chem       Date:  1984-06-10       Impact factor: 5.157

7.  Reporting results of cancer treatment.

Authors:  A B Miller; B Hoogstraten; M Staquet; A Winkler
Journal:  Cancer       Date:  1981-01-01       Impact factor: 6.860

8.  Inhibition of murine osteogenic sarcomas by treatment with type I or type II interferon.

Authors:  J L Crane; L A Glasgow; E R Kern; J S Youngner
Journal:  J Natl Cancer Inst       Date:  1978-09       Impact factor: 13.506

9.  Depressed natural killer cell activity in patients with hepatocellular carcinoma. In vitro effects of interferon and levamisole.

Authors:  K Son; M Kew; A R Rabson
Journal:  Cancer       Date:  1982-12-15       Impact factor: 6.860

  9 in total
  3 in total

1.  Rapid growth of hepatocellular carcinoma after or during interferon treatment of chronic hepatitis C: report of three cases.

Authors:  A Onitsuka; N Yamada; H Yasuda; T Miyata; T Kachi
Journal:  Surg Today       Date:  1996       Impact factor: 2.549

2.  Interferon-gamma and cytotoxic agents studied in combination using a soft agarose human tumor clonogenic assay.

Authors:  T Saito; M E Berens; C E Welander
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

3.  Intraarterial combined immunochemotherapy for unresectable hepatocellular carcinoma: preliminary results.

Authors:  M Oka; S Hazama; S Yoshino; K Shimoda; M Suzuki; R Shimizu; K Yano; M Nishida; T Suzuki
Journal:  Cancer Immunol Immunother       Date:  1994-03       Impact factor: 6.968

  3 in total

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