Literature DB >> 24131197

Impact of chlorhexidine cleansing of the umbilical cord on cord separation time and neonatal mortality in comparison to dry cord care - a nursery-based randomized controlled trial.

Deepak Sharma1, Geeta Gathwala.   

Abstract

AIM: To study the impact of chlorhexidine cleansing of the umbilical cord on cord separation time and neonatal mortality in comparison to dry cord care.
METHODS: This is the secondary analysis of the data of the study which was conducted in the NICU of a teaching hospital in north India between 2010 and 2011. Newborns (>32 weeks of gestation and weighing >1500 g) were randomized into chlorhexidine application and dry cord care groups. Here, we analyze the data regarding time of cord separation, umbilical sepsis and mortality in both the groups.
RESULTS: One hundred and forty (dry care group 70, chlorhexidine group 70) were enrolled and finally analyzed. A significant difference was observed among groups in terms of time to cord separation (8.92 ± 2.77 days versus 10.31 ± 3.23 days; t = 2.20; p = 0.02, significant) and neonatal mortality (χ(2) = 4.11; p = 0.042, significant).
CONCLUSION: Use of chlorhexidine for umbilical cord care shortens duration of cord separation and decreases neonatal mortality in NICU. This simple intervention can be used as mode for decreasing neonatal mortality.

Entities:  

Keywords:  Chlorhexidine; cord separation time; neonatal mortality; umbilical sepsis

Mesh:

Substances:

Year:  2013        PMID: 24131197     DOI: 10.3109/14767058.2013.854325

Source DB:  PubMed          Journal:  J Matern Fetal Neonatal Med        ISSN: 1476-4954


  3 in total

Review 1.  Umbilical cord cleansing with chlorhexidine in neonates: a systematic review.

Authors:  M J Sankar; A Chandrasekaran; A Ravindranath; R Agarwal; V K Paul
Journal:  J Perinatol       Date:  2016-05       Impact factor: 2.521

Review 2.  Golden hour of neonatal life: Need of the hour.

Authors:  Deepak Sharma
Journal:  Matern Health Neonatol Perinatol       Date:  2017-09-19

3.  Correlation of Apgar Score with Asphyxial Hepatic Injury and Mortality in Newborns: A Prospective Observational Study From India.

Authors:  Deepak Sharma; Mukesh Choudhary; Mamta Lamba; Sweta Shastri
Journal:  Clin Med Insights Pediatr       Date:  2016-05-10
  3 in total

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