Literature DB >> 24131076

Sympathetic ophthalmia in pediatric age group: clinical features and challenges in management in a tertiary center in southern India.

Kshitiz Kumar1, Annie Mathai, Somasheila I Murthy, Subhadra Jalali, Virender Sangwan, Rajeev Reddy Pappuru, Avinash Pathangay.   

Abstract

PURPOSE: To study the clinical features and visual outcome of sympathetic ophthalmia in pediatric patients attending a tertiary care center.
METHODS: Retrospective review of patients ≤16 years with sympathetic ophthalmia seen during the period 2001-2011.
RESULTS: During this period, 2511 pediatric patients with open globe injuries and 14 patients with sympathetic ophthalmia were seen. Six patients developed sympathetic ophthalmia during follow-up here. The incidence rate of sympathetic ophthalmia is 0.24% (6/2511, 95% CI:0.05-0.43%). The commonest presenting signs were anterior uveitis and exudative detachment. All patients were treated with systemic steroids, while 7 patients received additional immunosuppressive therapy. Eight patients had a follow-up of more than 6 months. Mean presenting best-corrected visual acuity (1.25 ± 1.03 logMAR) in the sympathizing eye improved significant following treatment (0.42 ± 0.80 logMAR, p = 0.003).
CONCLUSIONS: The incidence of sympathetic ophthalmia was 0.24%. Appropriate immunosuppression can lead to favorable visual outcomes in the sympathizing eye.

Entities:  

Keywords:  Exudative retinal detachment; immunosuppression; panuveitis; pediatric; sympathetic ophthalmia

Mesh:

Substances:

Year:  2013        PMID: 24131076     DOI: 10.3109/09273948.2013.841958

Source DB:  PubMed          Journal:  Ocul Immunol Inflamm        ISSN: 0927-3948            Impact factor:   3.070


  6 in total

1.  Postsurgical sympathetic ophthalmia: retrospective analysis of a rare entity.

Authors:  Parthopratim Dutta Majumder; Eliza Anthony; Amala Elizabeth George; Sudha K Ganesh; Jyotirmay Biswas
Journal:  Int Ophthalmol       Date:  2017-11-21       Impact factor: 2.031

2.  Sympathetic ophthalmia presenting 5 days after penetrating injury.

Authors:  Andrew M Williams; Anne M Shepler; Charleen T Chu; Ken K Nischal
Journal:  Am J Ophthalmol Case Rep       Date:  2020-07-09

3.  Sympathetic Ophthalmia: Experience from a Tertiary Care Center in Northern India.

Authors:  Rohan Chawla; Monika Kapoor; Aditi Mehta; Koushik Tripathy; Rajpal Vohra; Pradeep Venkatesh
Journal:  J Ophthalmic Vis Res       Date:  2018 Oct-Dec

4.  Sympathetic Ophthalmia in a 22-Month-Old Infant With Sturge-Weber Syndrome With Atypical Histopathological Correlation.

Authors:  Linda A Cernichiaro-Espinosa; Aaron S Gold; Audina M Berrocal; Sander R Dubovy; Ta Chen Chang; Abby Orcutt-Hayes; Timothy G Murray
Journal:  J Vitreoretin Dis       Date:  2018-06-20

Review 5.  Pediatric open globe injury: A review of the literature.

Authors:  Xintong Li; Marco A Zarbin; Neelakshi Bhagat
Journal:  J Emerg Trauma Shock       Date:  2015 Oct-Dec

6.  AN ATYPICAL CASE OF SYMPATHETIC OPHTHALMIA AFTER LIMBAL CORNEAL LACERATION.

Authors:  Praveen Subudhi; Sanghamitra Kanungo; B Nageswar Rao Subudhi
Journal:  Retin Cases Brief Rep       Date:  2017 Spring
  6 in total

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