Literature DB >> 24130983

Effect of pegylated hyaluronate-endo-β-N-acetylhexosaminidase on humoral mechanisms regulating the functions of progenitor cells during chronic hepatitis.

A M Dygai1, G N Zyuz'kov, R V Gurto, V V Zhdanov, E V Udut, L A Miroshnichenko, E V Simanina, L A Stavrova, A V Chaikovskiy, T S Markova, M Yu Minakova, P G Madonov, D N Kinsht, A V Artamonov, A A Bekarev.   

Abstract

We studied the effect of hyaluronate-endo-β-N-acetylhexosaminidase on the secretory function of the liver and bone marrow microenvironment cells in chronic hepatitis. Enhanced production of substances stimulating parenchymal tissue-specific precursors and stem cell homing factors by liver cells was revealed. At the same time, production of SDF-1 and other chemoattractants and adhesion factors of progenitor cells by bone marrow elements was reduced.

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Year:  2013        PMID： 24130983     DOI： 10.1007/s10517-013-2106-4

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  1 in total

1.  Postpartum Involution of Mouse Myometrium in Acute CCl4-Induced Hepatosis and Its Correction with Immobilized Hyaluronidase.

Authors:  A P Nadeev; P G Madonov; E V Porotnikova; K A Koshlich; A V Kuznetsov; E V Ovsyanko; L Yu Kostina; D Ya Yakuba
Journal:  Bull Exp Biol Med       Date:  2022-06-23       Impact factor: 0.804
  1 in total

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