Literature DB >> 2412934

Relation between inhibition of calmodulin and mediator release from rat mast cells.

K Ohishi, T Suzuki, M K Uchida.   

Abstract

Cationic drugs that interact with calmodulin such as chlorpromazine, trifluoperazine, W-7 and lidocaine caused dose-dependent release of mediator from rat mast cells. A significant correlation was observed between the effects of test drugs with different structure in causing mediator release and calmodulin inhibition.

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Year:  1985        PMID: 2412934     DOI: 10.1016/0306-3623(85)90192-2

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN: 0306-3623


  2 in total

1.  Effect of picumast on histamine release from rat cardiac and peritoneal mast cells.

Authors:  B Y Wan; K H Peh; E S Assem
Journal:  Agents Actions       Date:  1991-05

2.  Effects of calmodulin antagonists on human adenoidal mast cells.

Authors:  S Bent; U Braam; W Schmutzler
Journal:  Agents Actions       Date:  1990-04
  2 in total

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