Literature DB >> 24128093

Environmentally benign synthesis of indeno[1,2-b]quinolines via an intramolecular Povarov reaction.

Ming Chen1, Ning Sun, Yuanhong Liu.   

Abstract

A new synthetic route to indeno[1,2-b]quinolines via reactions of o-propargylbenzaldehydes with N-aryl amines based on an intramolecular aza-Diels-Alder (Povarov) reaction has been developed. This method offers several advantages such as no requirement for an oxidant, high efficiency, and a wide reaction scope.

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Year:  2013        PMID： 24128093     DOI： 10.1021/ol402775k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Oxone promoted dehydrogenative Povarov cyclization of N-aryl glycine derivatives: an approach towards quinoline fused lactones and lactams.

Authors:  Devidas A More; Ganesh H Shinde; Aslam C Shaikh; M Muthukrishnan
Journal:  RSC Adv       Date:  2019-09-25       Impact factor: 4.036

2.  Construction of Dispiro-Indenone Scaffolds via Domino Cycloaddition Reactions of α,β-Unsaturated Aldimines with 2-Arylidene-1,3-indenediones and 2,2'-(Arylmethylene)bis(1,3-indenediones).

Authors:  Wen-Juan Yang; Hui-Lin Fang; Jing Sun; Chao-Guo Yan
Journal:  ACS Omega       Date:  2019-08-07

3.  A dual role for acetohydrazide in Pd-catalyzed controlled C(sp3)-H acetoxylation of aldehydes.

Authors:  Juan Chen; Chaolumen Bai; XingWen Tong; Dan Liu; Yong-Sheng Bao
Journal:  RSC Adv       Date:  2020-03-25       Impact factor: 3.361

4.  One-Pot Cannizzaro Cascade Synthesis of ortho-Fused Cycloocta-2,5-dien-1-ones from 2-Bromo(hetero)aryl Aldehydes.

Authors:  Laurence Burroughs; Lee Eccleshare; John Ritchie; Omkar Kulkarni; Barry Lygo; Simon Woodward; William Lewis
Journal:  Angew Chem Int Ed Engl       Date:  2015-07-29       Impact factor: 15.336

5.  Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils.

Authors:  Dan E Adolfsson; Mohit Tyagi; Pardeep Singh; Adrian Deuschmann; Jörgen Ådén; Anna L Gharibyan; Sanduni Wasana Jayaweera; Anders E G Lindgren; Anders Olofsson; Fredrik Almqvist
Journal:  J Org Chem       Date:  2020-10-25       Impact factor: 4.354
  5 in total

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