Literature DB >> 24128077

Withanolide-based steroids from the cultured soft coral Sinularia brassica.

Chiung-Yao Huang1, Chih-Chuang Liaw, Bo-Wei Chen, Pei-Chin Chen, Jui-Hsin Su, Ping-Jyun Sung, Chang-Feng Dai, Michael Y Chiang, Jyh-Horng Sheu.   

Abstract

Seven novel withanolides, sinubrasolides A-G (1-7), have been isolated from the cultured soft coral Sinularia brassica. The structures of the new metabolites were determined by extensive spectroscopic analyses, and the absolute configuration of 1 was established by X-ray crystallographic analysis. The cytotoxicities of compounds 1-7 against a limited panel of cancer cell lines also were determined.

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Year:  2013        PMID： 24128077     DOI： 10.1021/np400454q

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Bioactive Steroids from the Formosan Soft Coral Umbellulifera petasites.

Authors:  Chiung-Yao Huang; Che-Wei Chang; Yen-Ju Tseng; Jessica Lee; Ping-Jyun Sung; Jui-Hsin Su; Tsong-Long Hwang; Chang-Feng Dai; Hui-Chun Wang; Jyh-Horng Sheu
Journal:  Mar Drugs       Date:  2016-10-11       Impact factor: 5.118

2.  New 1,4-Dienonesteroids from the Octocoral Dendronephthya sp.

Authors:  Thanh-Hao Huynh; Pei-Chin Chen; San-Nan Yang; Feng-Yu Lin; Tung-Pin Su; Lo-Yun Chen; Bo-Rong Peng; Chiung-Chin Hu; You-Ying Chen; Zhi-Hong Wen; Tung-Ying Wu; Ping-Jyun Sung
Journal:  Mar Drugs       Date:  2019-09-11       Impact factor: 5.118

Review 3.  Coral and Coral-Associated Microorganisms: A Prolific Source of Potential Bioactive Natural Products.

Authors:  Vo Thanh Sang; Ton That Huu Dat; Le Ba Vinh; Le Canh Viet Cuong; Phung Thi Thuy Oanh; Hoang Ha; Young Ho Kim; Hoang Le Tuan Anh; Seo Young Yang
Journal:  Mar Drugs       Date:  2019-08-11       Impact factor: 5.118

Review 4.  Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides.

Authors:  Amandeep Singh; Asif Raza; Shantu Amin; Chendil Damodaran; Arun K Sharma
Journal:  Molecules       Date:  2022-01-28       Impact factor: 4.411

Review 5.  Chemical Diversity and Biological Activity of Secondary Metabolites from Soft Coral Genus Sinularia since 2013.

Authors:  Xia Yan; Jing Liu; Xue Leng; Han Ouyang
Journal:  Mar Drugs       Date:  2021-06-11       Impact factor: 5.118

6.  Bioactive Steroids with Methyl Ester Group in the Side Chain from a Reef Soft Coral Sinularia brassica Cultured in a Tank.

Authors:  Chiung-Yao Huang; Jui-Hsin Su; Chih-Chuang Liaw; Ping-Jyun Sung; Pei-Lun Chiang; Tsong-Long Hwang; Chang-Feng Dai; Jyh-Horng Sheu
Journal:  Mar Drugs       Date:  2017-09-01       Impact factor: 5.118

Review 7.  Natural Withanolides in the Treatment of Chronic Diseases.

Authors:  Peter T White; Chitra Subramanian; Hashim F Motiwala; Mark S Cohen
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

8.  Isolation of Sesquiterpenoids and Steroids from the Soft Coral Sinularia brassica and Determination of Their Absolute Configuration.

Authors:  Giang Nam Pham; Da Yeun Kang; Min Ju Kim; Se Jong Han; Jun Hyuck Lee; MinKyun Na
Journal:  Mar Drugs       Date:  2021-09-17       Impact factor: 5.118
  8 in total

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