Literature DB >> 24127373

An unusually high troponin I result in association with Legionella infection.

Abhijit Gill1, Simon William Dubrey.   

Abstract

A 77-year-old man presented himself with shortness of breath that was initially felt to be due to an acute coronary event, largely due to a very elevated troponin I result and his medical history. He subsequently showed evidence to suggest a significant pneumonia. The most likely candidate organism responsible, from the history and test results, appeared to be Legionella. We present the case for a spuriously and extremely elevated troponin I result, being at least in part due the production of heterophil antibodies by Legionella.

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Year:  2013        PMID: 24127373      PMCID: PMC3822183          DOI: 10.1136/bcr-2013-200489

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  New and emerging etiologies for community-acquired pneumonia with implications for therapy. A prospective multicenter study of 359 cases.

Authors:  G D Fang; M Fine; J Orloff; D Arisumi; V L Yu; W Kapoor; J T Grayston; S P Wang; R Kohler; R R Muder
Journal:  Medicine (Baltimore)       Date:  1990-09       Impact factor: 1.889

Review 2.  Molecular pathogenesis of infections caused by Legionella pneumophila.

Authors:  Hayley J Newton; Desmond K Y Ang; Ian R van Driel; Elizabeth L Hartland
Journal:  Clin Microbiol Rev       Date:  2010-04       Impact factor: 26.132

3.  Heterophile antibodies produce spuriously elevated concentrations of cardiac Troponin I in patients with Legionella pneumophila.

Authors:  M Lucía García-Mancebo; M Teresa Agulló-Ortuño; Juan R Gimeno; M Dolores Navarro-Martínez; Joaquín Ruíz-Gómez; José A Noguera-Velasco
Journal:  Clin Biochem       Date:  2005-06       Impact factor: 3.281

Review 4.  Use and misuse of cardiac troponins in clinical practice.

Authors:  Sachin Gupta; James A de Lemos
Journal:  Prog Cardiovasc Dis       Date:  2007 Sep-Oct       Impact factor: 8.194

Review 5.  Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB.

Authors:  F S Apple
Journal:  Clin Chim Acta       Date:  1999-06-30       Impact factor: 3.786

6.  Fluctuation of spuriously elevated troponin I: a case report.

Authors:  Sam Ghali; Keith Lewis; Viviane Kazan; Neezam Altorok; Jamil Taji; Mohammad Taleb; Kiranmayee Lanka; Ragheb Assaly
Journal:  Case Rep Crit Care       Date:  2012-03-25
  6 in total

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